Gastro
01 Jan 2013
Obesity and Free Fatty Acid Flux
This study, conducted at the National Institutes of Health in Bethesda, Maryland, and at the Mayo Clinic in Rochester, Minnesota, will explore obesity among Caucasians and African-Americans by examining the relationship of resting energy expenditure (REE) to fatty acid flux. REE is the rate the body uses calories while at…
Heart
01 Jan 2013
Efficacy and Safety of Azimilide in the Prophylactic Treatment of Patients With Atrial Fibrillation.
Atrial fibrillation (an abnormal rhythm in the upper chamber of the heart) is a common supraventricular arrhythmia (a type of abnormal heart rhythm) for which antiarrhythmic therapy is often prescribed. The primary goals of therapy are to maintain sinus rhythm (normal heart rhythm) and to reduce the occurrence of episodes…
Heart
01 Jan 2013
Healthy Heart Amputation Rehabilitation Treatment (H.A.R.T)
In the VA, we are achieving progress in decreasing amputation rates through early identification and multidisciplinary treatment of patients at risk for limb loss. Despite these accomplishments, however, clinical outcomes post-amputation, especially for PVD patients, have changed little because of patients’ poor cardiovascular condition complicated by the injurious consequences of…
Cancer
01 Jan 2013
Surgery in Treating Children With Neuroblastoma
RATIONALE: Surgery alone may be effective in treating children with neuroblastoma. PURPOSE: Phase III trial to study the effectiveness of surgery alone in treating children who have neuroblastoma. Official Title Phase III Study of Primary Surgical Therapy in Children With Low-Risk Neuroblastoma Conditions – localized resectable neuroblastoma- stage 4S neuroblastoma…
Research and Trials
01 Jan 2013
Renal Allograft Recipients Study
To determine the effect of conversion from calcineurin inhibitor to sirolimus based therapy on renal function. Official Title A randomized, open-label, comparative evaluation of conversion from calcineurin inhibitors to sirolimus versus continued use of calcineurin inhibitors in renal allograft recipients. Conditions – Renal Allograft Recipients Study Type Interventional Study…
Cancer
01 Jan 2013
Assessing Quality of Life of Patients With Prostate Cancer
RATIONALE: Quality of life assessment in patients undergoing prostate cancer treatment may help determine the intermediate and long-term effects of the treatment on these patients. Official Title Study of the EORTC QLQ-C30 and Prostate Cancer-Specific QLQ-PR25 Questionnaires to Assess Quality of Life of Patients With Stage I-IV Prostate Cancer…
Cancer
01 Jan 2013
Prostatectomy Compared With Watchful Waiting in Treating Patients With Stage I or Stage II Prostate Cancer
RATIONALE: Watchful waiting until symptoms appear may be effective in patients with prostate cancer. It is not yet known if watchful waiting is more effective than prostatectomy for early prostate cancer. Official Title NCI HIGH PRIORITY CLINICAL TRIAL — Phase III Randomized Study of Prostatectomy Versus Expectant Management With Palliative…
Mental Health
01 Jan 2013
Therapeutic Processes and Treatment Outcome in Adolescents with Anxiety Disorders
The purpose of this study is to examine the relationship between different aspects of cognitive behavior therapy (CBT) and treatment outcome. Official Title Process as a Predictor of Outcomes in CBT for Youth Conditions – Anxiety Disorders Study Type Interventional Study Design Treatment, Non-Randomized, Open Label, Active Control, Single…
Cancer
01 Jan 2013
XELOX versus fluorouracil/leucovorin as therapy for surgery in association with colon carcinoma
The primary purpose of the study is to show that the combination of capecitabine plus oxaliplatin (XELOX) is better than the combination of fluorouracil/leucovorin (5-FU/LV) in terms of time to cancer relapse or death in patients who have had surgery for colon cancer (Dukes stage C) and have not received…
