Cancer
01 Jan 2013
Zileuton in Preventing Lung Cancer in Patients With Bronchial Dysplasia
RATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent the development or recurrence of cancer. The use of zileuton may be an effective way to prevent lung cancer in patients who have bronchialdysplasia. RATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent…
Cancer
01 Jan 2013
PS-341 Plus Carboplatin in Platinum and Taxane Resistant Recurrent Ovarian Cancer, Primary Peritoneal Cancer, and Fallopian Tube Cancer
The goal of this clinical research study is to find the highest safe dose of PS-341 that can be given with carboplatin chemotherapy as a treatment for patients with ovarian, abdominal, or fallopian tube cancer. Researchers also hope to find out if giving these drugs together will help shrink or…
Cancer
01 Jan 2013
Selenium and Vitamin E in Preventing Prostate Cancer
RATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent the development of cancer. It is not yet known which regimen of selenium and/or vitamin E may be more effective in preventing prostate cancer. RATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent…
Mental Health
01 Jan 2013
Vitamin E in Aging Persons With Down Syndrome
The goal of this study is to determine the safety and efficacy of the administration of vitamin E, which has been shown to delay the progression of Alzheimer’s disease, in slowing the rate of cognitive/functional decline in older persons with Down syndrome. Official Title Multicenter Vitamin E Trial in Aging…
Cancer
01 Jan 2013
Vaginal Changes and Sexual Function in Patients With Cervical Cancer
RATIONALE: Vaginal changes that may effect sexual function occur in patients undergoing treatment for cervical cancer. Official Title Conditions Study Type Study Design Further Details Study Start Eligibility & Criteria Total Enrolment Contact Details…
Infections
01 Jan 2013
Peg-Intron for Prevention of Disease Progression in Chronic Hepatitis C Patients with Cirrhosis who failed with a Interferon plus Ribavirin Therapy
The objective of the study is to evaluate the safety and efficacy of PEG-Intron vs. no treatment for the prevention of disease progression in adult subjects with compensated cirrhosis secondary to chronic hepatitis C, who failed to respond to therapy with an a interferon plus ribavirin. Official Title Conditions –…
Bone
01 Jan 2013
Diagnostic Study of Patients With Ewing’s Sarcoma
RATIONALE: Genetic testing may help predict how cancer will respond to treatment and allow doctors to plan more effective therapy. PURPOSE: Diagnostic trial to study genetic differences in patients who have Ewing’s sarcoma. RATIONALE: Genetic testing may help predict how cancer will respond to treatment and allow doctors to…
Heart
01 Jan 2013
A safety and efficacy trial evaluating the use of SanOrg34006 in the treatment of Deep Vein Thrombosis (DVT)
Patients who have deep vein thrombosis (blood clot in the leg) will be treated in this study. The purpose of the study is to compare the safety and effectiveness of a new injectible anticoagulant (blood thinning) drug administered once each week, SanOrg34006, with the standard way of treating deep vein…
Bone
01 Jan 2013
Spine Patient Outcomes Research Trial (SPORT) – Intervertebral Disc Herniation
This study tests the effectiveness of different treatments for the three most commonly diagnosed lumbar (lower) spine conditions. The purpose of the study is to learn which of two commonly prescribed treatments (surgery and non-surgical therapy) works better for specific types of low back pain. This study tests the effectiveness…
