Cancer
01 Jan 2013
Tumor Vaccine and Interferon gamma in Treating Patients With Refractory Epithelial Ovarian Cancer
RATIONALE: Vaccines made from a person’s cancer cells may make the body build an immune response to and kill their tumor cells. Combining vaccine therapy with interferon gamma may be a more effective treatment for epithelial ovarian cancer. RATIONALE: Vaccines made from a person’s cancer cells may make the body…
Cancer
01 Jan 2013
Combination Chemotherapy in Treating Patients With Liver Metastases from Colorectal Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells. It is not yet known which chemotherapy regimen is more effective for metastatic colorectal cancer. PURPOSE: Randomizedphase III trial…
Cancer
01 Jan 2013
Imiquimod in Preventing Cervical Cancer in Women With Cervical Neoplasia
RATIONALE: Chemoprevention therapy is the use of certain substances to try to prevent the development of cancer. Applying topicalimiquimod before abnormal cervical cells are removed may be effective in preventing cervical cancer. RATIONALE: Chemoprevention therapy is the use of certain substances to try to prevent the development of cancer. Applying…
Lungs
01 Jan 2013
Respiratory Syncytial Virus (RSV) Bronchiolitis Study
The purpose of this study is to look at whether an investigational drug can treat the breathing symptoms of RSV bronchiolitis in children 6 to 18 months of age. Official Title Conditions – Bronchiolitis Study Type Interventional Study Design Treatment, Randomized, Double-Blind, Placebo Control, Parallel Assignment, Safety/Efficacy Study…
Cancer
01 Jan 2013
Fruit and Vegetable Extracts in Treating Patients With Stage I, Stage II, or Stage III Head and Neck Cancer
RATIONALE: Chemoprevention therapy is the use of certain substances to try to prevent the development or recurrence of cancer. Fruit and vegetable extracts may be effective in preventing the recurrence or further development of head and neck cancer. RATIONALE: Chemoprevention therapy is the use of certain substances to try to…
Hormones
01 Jan 2013
Turner Syndrome: Genotype and Phenotype
This study will examine the clinical and genetic factors related to Turner syndrome, a disorder of the female sex chromosomes. Humans have 23 pairs of chromosomes-thin strands of DNA-in the nucleus of every cell, which contain genes that determine our hereditary makeup. One pair of chromosomes is the sex chromosomes,…
Heart
01 Jan 2013
Study of Triostat in Infants during Heart Surgery
This is a study to determine the safety and efficacy of liothyronine sodium/triiodothyronine (Triostat), a synthetic thyroid hormone, when given to infants with congenital heart disease during cardiopulmonary bypass surgery. Official Title Triostat in Children during CPB Conditions – Heart Defects, Congenital Study Type Interventional Study Design Treatment, Randomized,…
Heart
01 Jan 2013
Multidisciplinary Study of Right Ventricular Dysplasia
To investigate the cardiac, clinical, and genetic aspects of arrhythmogenic right ventricular dysplasia (ARVD), a progressive disorder that predominantly affects the right side of the heart and causes ventricular arrhythmias. Official Title Conditions – Heart Diseases- Ventricular Arrhythmia- Arrhythmogenic Right Ventricular Dysplasia Study Type Observational Study Design Natural History,…
Cancer
01 Jan 2013
Selenium in Preventing Cancer in Patients With Neoplasia of the Prostate
RATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent the development of cancer. The use of selenium may be an effective way to prevent prostate cancer in patients who have neoplasia of the prostate. PURPOSE: Randomizedphase III trial to study the effectiveness of selenium in…
