Infections
01 Jan 2013
Investigation of the Efficacy and Safety of Drotrecogin Alfa (Activated) in Pediatric Severe Sepsis.
The purposes of this study are to determine: 1. Whether drotrecogin alfa (activated) helps children with severe sepsis survive their condition more often or recover faster than children who do not receive drotrecogin alfa (activated). 2. Whether drotrecogin alfa (activated) minimizes long term disabilities associated with severe sepsis. 3.
Infections
01 Jan 2013
Increased Access to Emergency Contraceptive Pills
This study will evaluate the effect of easy access to emergency contraceptive pills (ECPs) on the rates of pregnancy and sexually transmitted infections (STIs). Official Title Conditions – Pregnancy- Sexually Transmitted Diseases Study Type Interventional Study Design Prevention, Randomized, Open Label, Active Control, Parallel Assignment, Safety/Efficacy Study Further Details…
Infections
01 Jan 2013
Cytotoxic T-Lymphocytes for the Prophylaxis of Cytomegalovirus after Allogeneic Stem Cell Transplant
Patients enrolled on this study have a type of blood cell cancer, other blood disease or a genetic disease for which they will receive a stem cell transplant. The donor of the stem cells will be either a brother or sister or another relative or a closely matched unrelated donor.
Hormones
01 Jan 2013
Long Term Post Operative Follow-Up of Cushing Syndrome
Although most patients with hypercortisolism can be diagnosed and treated the long-term effects of hypercortisolism and its treatment are unknown. Official Title Long-Term Post-Operative Follow-Up of Cushing Syndrome Conditions – Cushing Syndrome Study Type Observational Study Design Natural History Further Details This study will attempt to answer the following…
Infections
01 Jan 2013
Randomized Study of Two Doses of Oral Valacyclovir in Immunocompromised Patients With Uncomplicated Herpes Zoster
OBJECTIVES: I. Compare the efficacy and safety of two doses of oral valacyclovir in immunocompromised patients with uncomplicated herpes zoster. II. Compare quality of life, pain, and medical resource utilization in patients treated with these 2 regimens. OBJECTIVES:I. Compare the efficacy and safety of two doses of oral valacyclovir…
Infections
01 Jan 2013
HERPEVAC Trial for Women
The primary purpose of this study is to see if the vaccine is safe and prevents genital herpes disease in women who are not infected. The primary purpose of this study is to see if the vaccine is safe and prevents genital herpes disease in women who are not infected.
Infections
01 Jan 2013
Treating Severe Chronic EBV Infection with EBV Specific CTLs
Severe chronic active Ebstein-Barr virus (SCAEBV) is a rare Epstein-Barr virus (EBV or commonly known as mono or the kissing disease) associated disorder. This disorder may cause chronic tiredness and fevers and sometimes be complicated by life threatening problems such as multi-organ failure, chronic (ongoing) pneumonia, and lymphoproliferative diseases (diseases…
Blood
01 Jan 2013
Tipifarnib in Treating Patients With Myelofibrosis and Myeloid Metaplasia
RATIONALE: Tipifarnib may stop the growth of tumor cells by blocking the enzymes necessary for tumor cell growth. PURPOSE: Phase II trial to study the effectiveness of tipifarnib in treating patients who have myelofibrosis with myeloidmetaplasia. Condition: – chronic idiopathic myelofibrosis – Polycythemia Vera – Essential Thrombocythemia…
Infections
01 Jan 2013
Garlic in hyperlipidemia caused by HAART
This is a double-blind randomized placebo controlled trial to test the use of garlic to lower cholesterol and triglycerides in hyperlipidemic HIV-infected individuals who are being treated with highly active antiretroviral therapy (HAART). The garlic will be administered as enteric-coated tablets and in two escalating dosages. Condition: –…
