Research and Trials
01 Jan 2013
Study of Long-Term Living Kidney Donors
This study is designed to quantify the long-term medical and psychosocial implications of living kidney donation. The short-term consequences of living donation are well established. On the other hand the long-term consequences of living kidney donation are far less certain. The main medical concerns of living kidney donation include an…
Cancer
01 Jan 2013
SU011248 Versus Interferon-Alfa As First-Line Systemic Therapy For Patients With Metastatic Renal Cell Carcinoma
The purpose of this study is to test whether SU011248 has activity and is safe compared to interferon-alfa as first-line therapy in patients with metastatic renal cell carcinoma (RCC). Official Title A Phase 3, Randomized Study Of SU011248 Versus Interferon-Alfa As First-Line Systemic Therapy For Patients With Metastatic Renal Cell…
Research and Trials
01 Jan 2013
Using the Drug Spironolactone to Test If It Reduces Protein Leakage From the Kidney
The purpose of this study is to determine which combination of the tablets ramipril, irbesartan or spironolactone is best to lower protein leakage from the kidney. Protein leak from the kidney into the urine is an indicator of kidney damage. The higher the leak, the worse the damage and the…
Research and Trials
01 Jan 2013
Short Term Effects of FX Dialysers on QOL and Inflammation
This study aims to assess the short-term effects of the FX-class Dialyser on quality of life and inflammatory markers in stable haemodialysis patients with chronic kidney failure. Official Title Short-Term Effects of the FX-Class of Haemodialyser on Quality of Life and Inflammatory Markers in Stable Dialysis Patients. Conditions Kidney Failure,…
Blood
01 Jan 2013
A Prospective, Surveillance Study to Estimate the Incidence of Pure Red Blood Cell Aplasia (Aplastic Anemia) Mediated by Erythropoietin Antibodies Among Patients With Chronic Kidney Failure and Subcutaneous Exposure to Recombinant Erythropoietin Prod
The purpose of this study is to estimate the incidence rate of pure red cell aplasia (PRCA; aplastic anemia) mediated by erythropoietin (EPO) antibodies in patients who are receiving subcutaneous (s.c.) EPREX (polysorbate 80 formulation) for the treatment of anemia associated with chronic renal failure (CRF), and to compare this…
Heart
01 Jan 2013
ThromboEmbolism Prevention Efficacy and Safety Trial (TEMPEST)
The purpose of this study is to gain additional safety information as well as to determine after the study drug has been given to patients who have undergone total hip replacement surgery, whether the study drug is effective in preventing late deep vein thrombosis (blood clots in legs) or pulmonary…
Heart
01 Jan 2013
Lipitor In The Prevention Of Stroke, For Patients Who Have Had A Previous Stroke (SPARCL)
To determine whether Lipitor reduces stroke, compared to placebo in patients who have had a previous stroke or transient ischemic attack. Official Title A Double-Blind, Randomized, Placebo- Controlled Study Of Atorvastatin As Prevention Of Cerebrovascular Events In Patients With A Previous Transient Ischemic Attack (TIA) Or Stroke Conditions Stroke,…
Heart
01 Jan 2013
Can a Modified Fat Diet With Low Glycaemic Load Improve Insulin Sensitivity and Inflammatory Mediators in Overweight People With Chronic Heart Failure?
In overweight patients with chronic heart failure, to compare the effects of a modified fat diet with reduced glycaemic load (diet 1), and a conventional low fat, high carbohydrate diet (diet 2) on: insulin sensitivity (using the HOMA model); lipid profile; symptomatic status ( 6 minute walk distance and heart…
Heart
01 Jan 2013
‘CardioFit’ for the Treatment of Heart Failure
In this study, the safety and efficacy of a new vagus nerve stimulating system will be evaluated. This study will compare whether the new device improves Heart Failure parameters in Class II – III Heart Failure patients. Pharmacologic antagonism of the beta-adrenergic receptors shifting the autonomic balance in the…
