Research and Trials
01 Jan 2013
A Study to Evaluate AMG 162 in the Treatment of Postmenopausal Osteoporosis
This study will evaluate the effectiveness and safety of AMG 162 in treating women with Postmenopausal Osteoporosis. Official Title Conditions Osteoporosis Study Type Interventional Study Design Treatment Further Details Primary Outcome Measures: Reduction in the number of new vertebral fractures in post menopausal osteoporotic women treated with AMG…
Cancer
01 Jan 2013
GW786034 In Subjects With Locally Recurrent Or Metastatic Clear Cell Renal Cell Carcinoma
Phase II, multi-center, two-stage study utilising a randomised discontinuation design to evaluate the safety and efficacy of GW786034 in adult subjects with locally recurrent or metastatic clear-cell Renal Cell Carcinoma (RCC). Official Title A Phase II Study of GW786034 Using a Randomised Discontinuation Design in Subjects With Locally Recurrent or…
Hormones
01 Jan 2013
Comparison of Two Approaches to Insulin Therapy in Patients With Type 2 Diabetes
A study of patients with type 2 diabetes who are not controlled on two or more oral antihyperglycemic agents comparing adding insulin lispro mid mixture to the oral antihyperglycemic agents to adding insulin glargine to the oral antihyperglycemic agents. Official Title Comparison of Two Approaches to Basal-Bolus Insulin Therapy in…
Hormones
01 Jan 2013
Blood Pressure and Glucose Lowering for the Prevention of Vascular Disease in High Risk Patients With Type 2 Diabetes.
The purpose of this study is to provide information on the risks and benefits of routine blood pressure lowering (regardless of blood pressure level), and intensive lowering of blood glucose levels, in patients with Type 2 diabetes at high risk of cardiovascular events. The major outcomes of the study will…
Hormones
01 Jan 2013
Saxagliptin Treatment in Subjects With Type 2 Diabetes Who Are Not Controlled With Diet and Exercise
The purpose of this clinical research study is to learn whether Saxagliptin is more effective than placebo as a treatment for type 2 diabetic subjects who are not sufficiently controlled with diet and exercise. The safety of this treatment will also be studied. Official Title A Multicenter, Randomized, Double-Blind, Placebo-Controlled,…
Hormones
01 Jan 2013
E.V.O.L.V.E. Trial: EValuation Of Cinacalcet HCl Therapy to Lower CardioVascular Events
This study will evaluate the effects of cinacalcet (cincalcet HCl or Sensipar/Mimpara) on cardiovascular events and death in chronic kidney disease (CKD) patients with secondary hyperparathryoidism (HPT) who are receiving dialysis. Official Title EValuation Of Cinacalcet HCl Therapy to Lower CardioVascular Events Conditions Secondary Hyperparathyroidism, Chronic Kidney Disease Study Type…
Hormones
01 Jan 2013
Comparison of Insulin Detemir With NPH Insulin in Type 1 Diabetes
The aim of this research study is to compare the efficacy (reduction in HbA1c and in blood glucose levels) of insulin detemir compared to NPH insulin administered as basal insulin for the treatment of type 1 diabetes and to verify the safety of use (number and severity of episodes of…
Children's health
01 Jan 2013
Trial of Intranasal Insulin in Children and Young Adults at Risk of Type 1 Diabetes
In people with type I diabetes the beta cells of the pancreas no longer make insulin because the body’s immune system has attacked and destroyed the beta cells. It is thought that exposure of the mucous membranes to insulin may cause act like a vaccine effect whereby protective immune cells…
Research and Trials
01 Jan 2013
PROMPT Clinical Trial for Migraine Prevention
Various national and local guidelines demand revision of migraine prevention therapy after 4 to 6 months of treatment. However, there is no evidence from clinical studies to support the validity of such guidance. The PROMPT (PROlonged Migraine Prevention with Topiramate) study was set up to address this issue and evaluate…
