Research and Trials

Cancer 01 Jan 2013

Selenium and Vitamin E in Preventing Prostate Cancer

RATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent the development of cancer. It is not yet known which regimen of selenium and/or vitamin E may be more effective in preventing prostate cancer. RATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent…
Cancer 01 Jan 2013

Video-Assisted Surgery Followed by Radiation Therapy in Treating Patients With Stage I Non-small Cell Lung Cancer and Poor Heart and Lung Function

RATIONALE: Video-assisted surgery followed by radiation therapy may be an effective treatment in patients whose poor heart and lung function make them high risk for standard surgery. RATIONALE: Video-assisted surgery followed by radiation therapy may be an effective treatment in patients whose poor heart and lung function make them high…
Vitamin E in Aging Persons With Down Syndrome
Mental Health 01 Jan 2013

Vitamin E in Aging Persons With Down Syndrome

The goal of this study is to determine the safety and efficacy of the administration of vitamin E, which has been shown to delay the progression of Alzheimer’s disease, in slowing the rate of cognitive/functional decline in older persons with Down syndrome. Official Title Multicenter Vitamin E Trial in Aging…
Molecular Genetics of Schizophrenia
Mental Health 01 Jan 2013

Molecular Genetics of Schizophrenia

This study will orgnaize and release previously-obtained data from a DNA collection used to search for schizophrenia-related genes. The data will be made available to the scientific community for genetic studies of schizophrenia and related disorders. Official Title Conditions – Schizophrenia Study Type Observational Study Design Natural History…
Cancer 01 Jan 2013

Vaginal Changes and Sexual Function in Patients With Cervical Cancer

RATIONALE: Vaginal changes that may effect sexual function occur in patients undergoing treatment for cervical cancer. Official Title Conditions Study Type Study Design Further Details Study Start Eligibility & Criteria Total Enrolment Contact Details…
Infections 01 Jan 2013

Peg-Intron for Prevention of Disease Progression in Chronic Hepatitis C Patients with Cirrhosis who failed with a Interferon plus Ribavirin Therapy

The objective of the study is to evaluate the safety and efficacy of PEG-Intron vs. no treatment for the prevention of disease progression in adult subjects with compensated cirrhosis secondary to chronic hepatitis C, who failed to respond to therapy with an a interferon plus ribavirin. Official Title Conditions –…
Hormones 01 Jan 2013

Treatment of Peripheral Neuropathy in Patients with Diabetes.

The purpose of this protocol is to determine if an investigational drug is effective in treating nerve malfunction in diabetes. Condition: – Diabetic Neuropathies – Diabetes Mellitus The purpose of this protocol is to determine if an investigational drug is effective in treating nerve malfunction in diabetes.Condition: –…
Bone 01 Jan 2013

Diagnostic Study of Patients With Ewing’s Sarcoma

RATIONALE: Genetic testing may help predict how cancer will respond to treatment and allow doctors to plan more effective therapy. PURPOSE: Diagnostic trial to study genetic differences in patients who have Ewing’s sarcoma. RATIONALE: Genetic testing may help predict how cancer will respond to treatment and allow doctors to…
Abciximab (ReoPro) in Acute Ischemic Stroke
Heart 01 Jan 2013

Abciximab (ReoPro) in Acute Ischemic Stroke

Multinational, Multicenter, Randomized, Double-blind, Placebo-controlled trial to evaluate efficacy and safety of Abciximab in Acute Ischemic Stroke onset within 6 hour time window and subjects who wake from sleep with stroke symptoms, and in whom the planned treatment initiation is within 3 hours of awakening. Multinational, Multicenter, Randomized, Double-blind, Placebo-controlled…