Infections
01 Jan 2013
Resistance to HIV Infection
The immune systems of some individuals may be capable of resisting HIV infection. These individuals do not appear to be infected with HIV despite multiple sexual encounters with HIV infected partners. This study will examine the immune systems of these individuals to determine what factors are responsible for their ability…
Infections
01 Jan 2013
Immune Function of Infants with HIV
This observational study will evaluate data from infants born to HIV infected mothers in order to better characterize disease progression in early HIV infection. Official Title Killer Cells and Viral Load in Vertical HIV Infection Conditions HIV Infections Study Type Observational Study Design Natural History, Longitudinal, Defined Population, Retrospective/Prospective Study…
Heart
01 Jan 2013
Study of Triostat in Infants during Heart Surgery
This is a study to determine the safety and efficacy of liothyronine sodium/triiodothyronine (Triostat), a synthetic thyroid hormone, when given to infants with congenital heart disease during cardiopulmonary bypass surgery. Official Title Triostat in Children during CPB Conditions – Heart Defects, Congenital Study Type Interventional Study Design Treatment, Randomized,…
Heart
01 Jan 2013
Multidisciplinary Study of Right Ventricular Dysplasia
To investigate the cardiac, clinical, and genetic aspects of arrhythmogenic right ventricular dysplasia (ARVD), a progressive disorder that predominantly affects the right side of the heart and causes ventricular arrhythmias. Official Title Conditions – Heart Diseases- Ventricular Arrhythmia- Arrhythmogenic Right Ventricular Dysplasia Study Type Observational Study Design Natural History,…
Heart
01 Jan 2013
Cardiac Vulnerability in Potentially Susceptible Patients
This project is part of a program project directed toward assessing cardiac effects of particulate and other ambient air pollutants. In this project patient who have recently suffered a cardiac event are being monitored with cardiac monitors for 24 hours up to 4 times during the year following their cardiac…
Cancer
01 Jan 2013
Selenium in Preventing Cancer in Patients With Neoplasia of the Prostate
RATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent the development of cancer. The use of selenium may be an effective way to prevent prostate cancer in patients who have neoplasia of the prostate. PURPOSE: Randomizedphase III trial to study the effectiveness of selenium in…
Cancer
01 Jan 2013
Zileuton in Preventing Lung Cancer in Patients With Bronchial Dysplasia
RATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent the development or recurrence of cancer. The use of zileuton may be an effective way to prevent lung cancer in patients who have bronchialdysplasia. RATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent…
Cancer
01 Jan 2013
PS-341 Plus Carboplatin in Platinum and Taxane Resistant Recurrent Ovarian Cancer, Primary Peritoneal Cancer, and Fallopian Tube Cancer
The goal of this clinical research study is to find the highest safe dose of PS-341 that can be given with carboplatin chemotherapy as a treatment for patients with ovarian, abdominal, or fallopian tube cancer. Researchers also hope to find out if giving these drugs together will help shrink or…
Infections
01 Jan 2013
Antibody Production in Immune Disorders
This study will evaluate immune function in people with a known or suspected immune disorder. It will determine participants’ immune response to vaccines by measuring blood antibody levels after vaccination. Official Title Evaluation of Antibody Production in Primary Immune Disorders Conditions – Immunologic Disease Study Type Observational Study Design Natural…
