Blood
01 Jan 2013
Treatment of Deficient Subclass or Anti-Polysaccharide Antibody Response (Subklasse)
There is no consensus on the treatment of patients with recurrent infections and isolated immunoglobulin G (IgG)-subclass deficiency and/or selective antipolysaccharide antibody deficiency. Therefore, the Dutch Inter University Working Party will start a study in which the treatment with antibiotics is compared with intravenous immunoglobulin therapy with respect to clinical…
Research and Trials
01 Jan 2013
Efficacy Study of the Vaginal Gel Carraguard to Prevent HIV Transmission
The purposes of this study are to determine whether Carraguard® Gel can prevent the transmission of HIV when used during vaginal intercourse, and to confirm that the gel is safe for vaginal use. Official Title Phase 3 Study of the Efficacy and Safety of the Microbicide Carraguard® in Preventing…
Heart
01 Jan 2013
The Study of Atherosclerosis with Ramipril and Rosiglitazone
The purpose of this study is to determine if ramipril and/or rosiglitazone retard the progression of atherosclerosis as evaluated by serial carotid intermedial thickness measurements. Official Title The Study of Atherosclerosis With Ramipril and Rosiglitazone. Conditions Atherosclerosis Impaired Glucose Tolerance Isolated Impaired Fasting Glucose Cardiovascular Disease Study Type…
Heart
01 Jan 2013
The DIAMOND Study: Distensibility Improvement and Remodeling in Diastolic Heart Failure
The purpose of this study is to test the hypothesis that treatment with oral ALT-711 twice daily for 16 weeks will improve aortic distensibility, exercise tolerance, and quality of life in elderly patients with isolated diastolic heart failure (DHF), and that the improvements in exercise tolerance will correlate with the…
Cancer
01 Jan 2013
CyberKnife Radiosurgery for Organ-Confined Prostate Cancer: Homogenous Dose Distribution
The purpose of this study is to determine the effects of CyberKnife radiosurgery in patients with early stage organ-confined prostate cancer. Official Title Prospective Evaluation of CyberKnife Stereotactic Radiosurgery for Low and Intermediate Risk Prostate Cancer: Homogenous Dose Distribution. Conditions Prostate Cancer Prostatic Cancer Prostate Neoplasms…
Cancer
01 Jan 2013
AZD0530 Phase II Study in Patients With Advanced Ovarian Cancer (OVERT-1)
The main purpose of this study is to determine if AZD0530 can improve the efficacy of standard chemotherapy for the treatment of ovarian cancer. Official Title A Phase II, Double-Blind, Placebo-Controlled, Multi-Centre, Randomised Study of AZD0530 in Patients With Advanced Ovarian Cancer Sensitive to Platinum-Based Chemotherapy. Conditions…
Cancer
01 Jan 2013
Diagnostic Study of Patients With Stage I Testicular Cancer
Rationale: Diagnostic procedures may improve a doctor’s ability to predict the recurrence of testicular cancer.Purpose: Diagnostic trial to detect the risk of recurrent disease in patients who have stage I testicular cancer and who have undergone orchiectomy within the previous 12 weeks. Official Title Correlation of Histopathology, Immunohistochemistry and Quantitative…
Heart
01 Jan 2013
An Investigation of N-Acetylcysteine and Fenoldopam as Renal Protection Agents for Cardiac Surgery
Patients with abnormal kidney function are at increased risk for complications following heart surgery, including worsening kidney function possibly requiring dialysis, a prolonged stay in the critical care unit and hospital, and the increased risk of death. Prior attempts at kidney protection for heart surgery patients have had mixed results.
Research and Trials
01 Jan 2013
The Role of Reactive Oxygen Species in Ischaemia-Reperfusion Injury of the Transplanted Kidney
Measurement of reactive oxygen species production and antioxidant system status before and directly after reperfusion of the transplanted kidney and influence of oxidant stress on kidney function in 2 and 6 weeks.
Official TitleThe Role of Reactive Oxygen Species in Ischaemia-Reperfusion Injury of the Transplanted Kidney.
