Gastro
01 Jan 2013
Computer Intervention for Prevention of Weight Regain
Many overweight patients are able to lose weight successfully, but then regain their weight. The purpose of this study is to develop and test the efficacy of 2 interventions to prevent weight regain in individuals who have recently lost weight. The two interventions being tested are a face-to-face group maintenance…
Infections
01 Jan 2013
Safety and Efficacy Study of RTS,S AS02A/AS01B Vaccine to Prevent Malaria
This is a double blinded study where 2 test vaccines will be evaluated to see if they protect persons who have never had malaria against malaria infection when bitten by mosquitoes. Official Title Conditions Malaria Study Type Intervention Study Design Prevention, Randomized, Double-Blind, Active Control, Single Group Assignment, Safety/Efficacy Study…
Neurology
01 Jan 2013
Magnetic Resonance Spectroscopy to Evaluate Tourette’s Syndrome
This study will use magnetic resonance imaging (MRI) and magnetic resonance spectroscopy (MRS) of the brain to try to gain a better understanding of the disease process in Tourette’s syndrome, a neuropsychiatric disorder characterized by motor and vocal tics. Tourette’s syndrome is also associated with behavioral and emotional disturbances, including…
Mental Health
01 Jan 2013
Characterization of Childhood-Onset Obsessive-Compulsive Disorder
The purpose of this study is to learn more about Obsessive-compulsive Disorder (OCD) in children. OCD usually has a slow onset, and symptoms that may remain at a stable level over time. A subset of children with OCD has a sudden onset and symptoms that fluctuate in severity over time.
Cancer
01 Jan 2013
Exemestane Compared With Anastrozole, With or Without Celecoxib, in Treating Postmenopausal Women After Surgery for Primary Breast Cancer
RATIONALE: Estrogen can stimulate the growth of breast cancer cells. Hormone therapy using exemestane or anastrozole may fight breast cancer by reducing the production of estrogen. It is not yet known whether exemestane is more effective than anastrozole, with or without celecoxib, in preventing the recurrence of breast cancer. RATIONALE:…
Cancer
01 Jan 2013
Risedronate Sodium on Bone in Postmenopausal Women with Hormone-Receptor-Positive Early Breast Cancer
The purpose of this study is to evaluate safety parameters of anastrozole with regard to its potential effects on postmenopausal bone loss and on lipid profiles. This trial is conducted to investigate the effects of risedronate on BMD and on bone metabolism in postmenopausal women using anastrozole as adjuvant therapy…
Cancer
01 Jan 2013
Adjuvant Tamoxifen Compared With Anastrozole in Treating Postmenopausal Women With Ductal Carcinoma In Situ
RATIONALE: Estrogen can stimulate the growth of breast cancer cells. Hormone therapy using either tamoxifen or anastrozole may fight breast cancer by blocking the uptake of estrogen. It is not yet known whether tamoxifen is more effective than anastrozole in preventing breast cancer after surgery for ductal carcinoma in situ.
Mental Health
01 Jan 2013
Clonazepam and Paroxetine for Rapid Treatment of Post-Traumatic Stress Disorder
Post-Traumatic Stress Disorder (PTSD) is an anxiety disorder that follows exposure to an extremely traumatic stressors. PTSD is associated with serious symptoms. While numerous approaches have been used to treat PTSD, these treatments have several limiting factors. This study will evaluate a combination of the drugs clonazepam and paroxetine for…
Mental Health
01 Jan 2013
Effects of Arousal and Stress in Anxiety
This study has several parts. One part will examine the influence of factors such as personality and past experience on reactions to unpleasant stimuli. Others will examine the effect of personality and emotional and attentional states on learning and memory. Official Title Effects of Arousal and Stress on Classical Conditioning…
