Research and Trials

Cancer 01 Jan 2013

Hair Loss through Chemotherapy & Feminity in Young Women

Aim: To explore the impacts of hair loss, through chemotherapy, on young women’s sense of femininity. Official Title Hair Loss through Chemotherapy: How Does It Affect A Young Person’s Sense Of Femininity? Conditions Study Type Exploratory Study Design This 4th year honours project is seeking assistance from 6 young female…
Post-Operative Pain Management in Patients Undergoing Uterine Artery Embolisation for Symptomatic Leiomyomata
Research and Trials 01 Jan 2013

Post-Operative Pain Management in Patients Undergoing Uterine Artery Embolisation for Symptomatic Leiomyomata

This project seeks to evaluate the effectiveness of a new post-operative pain relief program for women who have undergone uterine artery embolisation (UAE). UAE is performed by an interventional radiologist as a treatment of uterine fibroids (non-cancerous growths of the uterus.) UAE can be associated with a high level…
ZD4054 in Pain-Free or Mildly Symptomatic Patients With Prostate Cancer and Bone Metastases Who Have Rising Serum Prostate Specific Antigen (PSA)
Cancer 01 Jan 2013

ZD4054 in Pain-Free or Mildly Symptomatic Patients With Prostate Cancer and Bone Metastases Who Have Rising Serum Prostate Specific Antigen (PSA)

This study is being carried out to see if ZD4054 is effective in treating prostate cancer and spread of cancer to the bone, and if so, how it compares with placebo (sugar pill). The study will also provide further information on the safety of ZD4054. Official Title Randomized, Double-Blind, Parallel-Group,…
Combination Chemotherapy and Radiation Therapy in Treating Patients With Acute Lymphoblastic Leukemia That Has Relapsed in the CNS or Testes
Cancer 01 Jan 2013

Combination Chemotherapy and Radiation Therapy in Treating Patients With Acute Lymphoblastic Leukemia That Has Relapsed in the CNS or Testes

Rationale: Drugs used in chemotherapy work in different ways to stop cancer cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage cancer cells. Giving combination chemotherapy together with radiation therapy may kill more cancer cells. Purpose: This clinical trial is…
Study In People With Type 2 Diabetes
Research and Trials 01 Jan 2013

Study In People With Type 2 Diabetes

Primary Outcomes: Improvement in glucose control over a 16 week period. Secondary Outcomes: Cholesterol, additional glycemic endpoints, safety endpoints. Official Title A Multicenter, Randomized, Double-Blind, Double-Dummy, Parallel-Group, Placebo-Controlled, Study To Evaluate Efficacy, Safety And Tolerability Of Oral GW677954 Capsules (2.5, 5, 10, 15 And 20 Mg Once A Day)…
Hormones 01 Jan 2013

Natural History Study of the Development of Type 1 Diabetes

The accrual of data from the laboratory and from epidemiologic and prevention trials has improved the understanding of the etiology and pathogenesis of type 1 diabetes mellitus (T1DM). Genetic and immunologic factors play a key role in the development of T1DM, and characterization of the early metabolic abnormalities in T1DM…
A Study of the Effectiveness and Safety of Dapoxetine in the Treatment of Men With Premature Ejaculation
Men's Health 01 Jan 2013

A Study of the Effectiveness and Safety of Dapoxetine in the Treatment of Men With Premature Ejaculation

Medical information about Dapoxetine in the Treatment of Men With Premature Ejaculation
Impact of Tight Glycaemic Control in Acute Myocardial Infarction
Research and Trials 01 Jan 2013

Impact of Tight Glycaemic Control in Acute Myocardial Infarction

Primary Outcomes: Difference in the change in wall motion score index between admission, day 3-5 and after 3 months in the two treatment arms. Secondary Outcomes: Changes in inflammatory/endothelial markers and myocardial perfusion from admission, day 3-5 and after 3 months between the two treatment arms. Researchers will randomise…
Bone 01 Jan 2013

Treatment of osteosarcoma at first recurrence after contemporary therapy

Aim: To determine the outcome for patients with recurrent OS who were treated at MSKCC at the time of first recurrence. Conclusions: At first recurrence, 22 of 31 patients achieved a CR2 with aggressive surgery and chemotherapy. The majority of these patients subsequently developed a disease recurrence. Patients appeared to…