Research and Trials
01 Jan 2013
Neurobiological Predictors of Huntington’s Disease (PREDICT-HD)
The purpose of this trial is to study early brain and behavioral changes in people who have the gene expansion for Huntington’s disease, but are currently healthy and have no symptoms. Official Title Neurobiological Predictors of Huntington’s Disease Trial Conditions Huntington Disease Study Type Observational Study Design Natural History Further…
Chronic Pain
01 Jan 2013
Efficacy Of Pregabalin In Subjects With Post-Stroke Pain
Efficacy of pregabalin in subjects with post-stroke pain. Official Title A 13-Week, Randomized, Multi-Centre, Double-Blind, Placebo-Controlled, Parallel-Group, Phase IV Study To Evaluate The Efficacy, Safety And Tolerability Of Pregabalin (150-600 Mg/Day) Using A Flexible Dosing Schedule In The Treatment Of Subjects With Central Post-Stroke Pain (CPSP). Conditions Central Nervous…
Cancer
01 Jan 2013
New Treatments for Prostate Cancer-How Do I Choose?
The many new treatments now available for localised prostate cancer make it more difficult to choose which is the best treatment. Options include radical prostatectomy in all its various forms, including nerve-sparing, non-nerve-sparing and non-nerve-sparing with sural nerve graft and robotic assisted laparoscopic surgery. It also includes conformal external beam…
Research and Trials
01 Jan 2013
A Study of the Effectiveness of Virtual Reality Relaxation Combined With Patient-Controlled Analgesia (PCA) Morphine for Those Undergoing Burn Dressing Changes
The purpose of this study is to evaluate whether a sub-population of patients with burn injuries needing dressing changes respond to virtual reality (VR) utilising relaxation themes with improved pain and anxiety scores, when added to PCA morphine and background analgesic therapy. Official Title Predicting the Effectiveness of Virtual Reality…
Cancer
01 Jan 2013
Study to Determine the Safety of Two Applications of PEP005 Topical Gel to Nodular Basal Cell Carcinoma.
The purpose of this study is to determine whether topical application of PEP005 is safe for the treatment of nodular basal cell carcinoma. Official Title A Multi-Center, Randomized, Double-Blind, Parallel-Group, Vehicle-Controlled Study to Determine the Safety of PEP005 0.0025%, 0.01% and 0.05% Gel With Two Treatment Schedules, Day 1 &…
Cancer
01 Jan 2013
PI-88 and/or Dacarbazine in Treating Patients With Metastatic Melanoma That Cannot Be Removed By Surgery
PI-88 may stop the growth of tumour cells by blocking blood flow to the tumour. Drugs used in chemotherapy, such as dacarbazine, work in different ways to stop the growth of tumour cells, either by killing the cells or by stopping them from dividing. Giving PI-88 together with dacarbazine may…
Research and Trials
01 Jan 2013
The Efficacy of a Pseudoallergen-Free Diet in the Treatment of Chronic Idiopathic Urticaria and/or Angioedema
This study involves investigating the effects of a pseudoallergen-free (active) diet compared with a control (placebo) diet in the treatment of Chronic Idiopathic Urticaria (CIU) and/or Angioedema. The hypothesis is that over a four-week intervention period, the pseudoallergen-free diet will be more effective than the placebo diet in reducing the…
Research and Trials
01 Jan 2013
Formation and Severity of Pressure Ulcers Associated With 4% Albumin Vs. 0.9% Sodium Chloride
Pressure ulcers incur multiple risks to the patient. The disruption of the skin is a portal of entry for infection, which may remain localised to the site or become blood borne. A pressure ulcer can lead to protein and fluid losses from the wound exudate. Many authors have theorised the…
Research and Trials
01 Jan 2013
Study Evaluating Etanercept on Skin and Joint Disease in Psoriatic Arthritis
To assess the efficacy of two different treatment regimens of etanercept in psoriasis subjects with psoriatic arthritis with respect to both the skin and joint manifestations. Official Title A Randomized, Double-Blind, Two-Period Study to Evaluate the Safety and Efficacy of Etanercept on Skin and Joint Disease in Psoriasis Subjects With…
