Cancer
01 Jan 2013
Vaccination Therapy in Treating Patients With Limited-Stage Small Cell Lung Cancer
Randomized phase III trial to compare the effectiveness of vaccination with monoclonal antibody BEC2 and BCG with that of no further therapy in treating patients who have limited-stage small cell lung cancer. Official Title The SILVA Study: Survival in an International Phase III Prospective Randomized LD Small Cell Lung Cancer…
Cancer
01 Jan 2013
A Clinical Trial of MK0683 in Combination With FDA Approved Cancer Drugs in Patients With Advanced Non-Small Cell Lung Cancer (NSCLC)
This clinical trial will determine the survival of advanced Non-small cell lung cancer patients when treated with MK0683 and paclitaxel plus carboplatin Official Title A Phase II/III Randomized, Double-Blind Study of Paclitaxel Plus Carboplatin in Combination With Vorinostat or Placebo in Patients With Stage IIIB (With Pleural Effusion) or…
Cancer
01 Jan 2013
A Study of Xeloda (Capecitabine) Plus Oxaliplatin in Patients With Colon Cancer
This study will compare the efficacy and safety of intermittent oral Xeloda plus Eloxatin with that of fluorouracil/leucovorin in patients who have had surgery for colon cancer and no previous chemotherapy. The anticipated time on study treatment is until disease progression and the target sample size is 500+ individuals. Official…
Cancer
01 Jan 2013
Pilot Efficacy Study of PI-88 With Docetaxel to Treat Prostate Cancer
Docetaxel (Taxotere) is an approved chemotherapeutic drug for the treatment of androgen-independent prostate cancer. The aim of the study is to investigate whether addition of the investigational drug PI-88 will increase the efficacy of docetaxel in this disease. PI-88 inhibits cancer growth by inhibiting the development of new blood vessels…
Cancer
01 Jan 2013
A Multi-Center Study of E7389 Versus Treatment of Physician’s Choice in Patients With Locally Recurrent or Metastatic Breast Cancer
The primary objective of this study is to compare Overall Survival (OS) in patients treated with E7389 versus the Treatment of Physician’s Choice (TPC) in patients with locally recurrent or metastatic breast cancer. Secondary objectives are to assess: Progression Free Survival (PFS) Objective Tumor Response Rate as measured…
Gastro
01 Jan 2013
Study Comparing Tigecycline Versus Ceftriaxone Sodium Plus Metronidazole in Complicated Intra-Abdominal Infection (cIAI)
This is a study of the safety and efficacy of tigecycline to ceftriaxone sodium plus metronidazole in hospitalized subjects with cIAI. Subjects will be followed for efficacy through the test-of-cure assessment. Safety evaluations will occur through the treatment and post-treatment periods and continue through resolution or stability of the adverse…
Children's health
01 Jan 2013
Hib-MenCY-TT Vaccine Study Compared to Licensed Hib and Meningococcal Serogroup C Conjugate Vaccines
This study is evaluating the safety and immunogenicity of Hib-MenCY-TT vaccine compared to control groups receiving licensed Hib or MenC conjugate vaccines, each administered at 2, 4, 6, and 12 to 15 months of age. Co-administration with live, attenuated measles, mumps, and rubella combination vaccine; and with live, attenuated varicella…
Infections
01 Jan 2013
Venticute in Patients With Pneumonia or Aspiration of Gastric Contents and Intubation/Ventilation/Oxygenation Impairment
Study to demonstrate that administration of Venticute increases survival of patients with pneumonia or aspiration of gastric contents leading to intubation, mechanical ventilation, and severe oxygenation impairment. Official Title Venticute in Patients With Pneumonia or Aspiration of Gastric Contents Leading to Intubation, Ventilation, and Severe Oxygenation Impairment: A Randomized, Multinational,…
Research and Trials
01 Jan 2013
Pneumococcal Vaccination of Australian Indigenous Mothers to See If It Protects Their Babies From Ear Disease
PneuMum: A Randomised Controlled Trial of Pneumococcal Polysaccharide Vaccination for Aboriginal and Torres Strait Islander Mothers to Protect Their Babies From Ear Disease clinical trials…
