Mental Health
01 Jan 2013
Deep Brain Stimulation for Parkinson’s Disease Trial
The purpose of this trial is to evaluate the effect of deep brain stimulation in the the globus pallidus (Gpi) and the subthalamic nucleus (STN) on motor, neuropsychological and psychiatric function, and quality of life in patients with Parkinson’s disease. Official Title Deep Brain Stimulation for Parkinson’s Disease Trial.
Blood
01 Jan 2013
Characteristics of Blood-Brain Barrier Permeability in Neurological Patients
The main goal of the present study is to challenge the hypothesis that blood-brain barrier disruption following brain injury increases the risk for long-term disability, development of brain dysfunction, epileptic seizures and neuroanatomical alterations. Official Title Blood-Brain Barrier Permeability in Neurological Patients: Anatomical, Neurophysiological, and Clinical Characteristics. Conditions Traumatic…
Mental Health
01 Jan 2013
Depressive Disorders and Normal Reactions to Negative Life Events
You are invited to take part in a research study into depression, sadness, and negative life events. We are interested in the relationships between the negative life events that people experience and their emotional state. Sadness is a common response to loss, and can involve low mood, disruption of eating…
Children's health
01 Jan 2013
An Effectiveness and Safety Study of ‘CONCERTA’ (Methylphenidate Hydrochloride) in the Treatment of Adolescents With Attention Deficit Hyperactivity Disorder
The purpose of this study is to evaluate the safety and effectiveness of CONCERTA (methylphenidate hydrochloride, a central nervous system (CNS) stimulant) versus placebo for the treatment of Attention Deficit Hyperactivity Disorder (ADHD) in adolescents. Official Title An Evaluation of the Safety and Effectiveness of CONCERTA (Methylphenidate Hydrochloride), up to…
Mental Health
01 Jan 2013
Multicomponent Risk Factor Intervention for People With a Severe Mental Illness: a Feasibility Study
This study is a feasibility study of a multi-component intervention to enhance healthy living among young people with psychotic disorders, specifically targeting smoking and weight. Official Title Multicomponent Risk Factor Intervention for People With a Severe Mental Illness: a Feasibility Study Conditions Psychotic Disorder Obesity Addictive Behavior Study Type Interventional…
Mental Health
01 Jan 2013
Genetics of Obsessive-Compulsive Disorder
The purpose of this study is to identify genes that affect susceptibility to obsessive-compulsive disorder (OCD). By identifying genes that increase or decrease the risk of OCD, researchers can better understand how the condition develops and ultimately improve treatment for people with OCD. Official Title Genetics of Obsessive-Compulsive Disorder: A…
Mental Health
01 Jan 2013
Use of Quetiapine as an Add on Therapy in the Treatment of Post Traumatic Stress Disorder
The purpose of this study is to evaluate how effective quetiapine versus placebo is when added to an existing therapy, in reducing the symptoms of PTSD. Official Title A Multicentre, Parallel Group, Randomised, Double Blind, Placebo Controlled Study of the Use of Quetiapine as an Add on Therapy in the…
Mental Health
01 Jan 2013
Efficacy of Seroquel SR in Combination With an Antidepressant in Treatment of Major Depressive Disorder (ONYX)
To evaluate the efficacy of quetiapine fumarate sustained release (Seroquel SR) in combination with an antidepressant versus an antidepressant alone in patients with Major Depressive Disorder. Official Title A Multi-Centre, Double-Blind, Randomised, Parallel-Group, Placebo-Controlled Phase III Study of the Efficacy and Safety of Quetiapine Fumarate Sustained Release (Seroquel SRTM) in…
Mental Health
01 Jan 2013
The Use of Selective Estrogen Receptor Modulators in the Treatment of Schizophrenia- a Pilot Study
The aim of the project is to investigate the use of raloxifene (a new form of estrogen) as a treatment for schizophrenia in postmenopausal women. Official Title The Use of Selective Estrogen Receptor Modulators in the Treatment of Schizophrenia- a Pilot Study Conditions Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorder Study Type…
