Bone

Vitamin D for preemies
Bone 31 May 2013

Vitamin D for preemies

Preterm infants may need to be given 800 international units (IU) of vitamin D a day to ensure they develop strong bones, according to a study to be presented Sunday, May 5, at the Pediatric Academic Societies (PAS) annual meeting in Washington, DC.   Preemies are known to be at…
Young runners, are you wearing the right running shoe?
Bone 30 Mar 2013

Young runners, are you wearing the right running shoe?

Many of today’s running shoes feature a heavy cushioned heel. New research presented at the 2013 Annual Meeting of the American Academy of Orthopaedic Surgeons(AAOS) found that these shoes may alter an adolescent runner’s biomechanics (the forces exerted by muscles and gravity on the skeletal structure) and diminish performance. Researchers…
Childhood ACL injuries need special care to avoid future problems
Bone 22 Feb 2013

Childhood ACL injuries need special care to avoid future problems

Until a child’s bones have fully matured (in girls, typically by age 14; in boys, age 16), an injury to the anterior cruciate ligament (ACL)—the primary, stabilizing ligament of the knee joint—requires special consideration, treatment and care to ensure appropriate healing and to prevent long-term complications. According to a review…
Bone 01 Jan 2013

Effect of Growth Hormone on Bone Metabolism in Anorexia Nervosa

Decreased bone strength is a serious medical problem present in many women with Anorexia Nervosa, or disordered eating. Women with weaker bones are more likely to suffer broken bones than women with normal bone strength. We are investigating whether a hormone that is naturally produced by the human body, called…
Bone 01 Jan 2013

Growth Hormone Therapy in Osteogenesis Imperfecta

Growth deficiency is a key feature of severe Osteogenesis Imperfecta (OI) and a frequent feature of mild to moderate forms of the disease. The reason that children with OI are short is not fully understood. We do know that details such as the number of fractures suffered or the type…
Bone 01 Jan 2013

Hypovitaminosis D and an Inadequate PTH Response in Chronic Liver Disease Patients

The purpose of this study is to determine how common low levels of magnesium are in patients with end stage liver disease. In addition, investigator is trying to determine if low levels of magnesium affect the release of parathyroid hormone in patients with end stage liver disease and low vitamin…
A Phase III Trial to Evaluate the Effectiveness and Safety of Tapentadol(CG5503) Extended Release (ER) in Patients With Moderate to Severe Chronic Pain Due to Osteoarthritis of the Knee
Bone 01 Jan 2013

A Phase III Trial to Evaluate the Effectiveness and Safety of Tapentadol(CG5503) Extended Release (ER) in Patients With Moderate to Severe Chronic Pain Due to Osteoarthritis of the Knee

The purpose of this trial is to evaluate the effectiveness (level of pain control) and safety of orally administrated CG5503 Extended Release (ER) (base) at doses of 100-250 mg twice daily in patients with moderate to severe chronic pain due to osteoarthritis of the knee, in comparison with placebo and…
Bone 01 Jan 2013

Pamidronate to Treat Osteogenesis Imperfecta in Children

This study will evaluate the effect of pamidronate-a drug that decreases bone resorption (breakdown)-on osteogenesis imperfecta. This is a genetic disorder of collagen, the major protein in bone. The abnormal collagen causes weak bones, and children with severe osteogenesis imperfecta sustain many fractures throughout their lives. They also have growth…
Bone 01 Jan 2013

Music in Reducing Anxiety and Pain in Adult Patients Undergoing Bone Marrow Biopsy for Haematologic Cancers or Other Diseases

Rationale:Listening to relaxing music during a bone marrow biopsy may be effective in reducing anxiety and pain.Purpose:This randomised clinical trial is studying how well music works in reducing anxiety and pain in adult patients undergoing bone marrow biopsy for haematologic cancers or other diseases. Official Title Use of Music to…