Blood
01 Jan 2013
Tipifarnib in Treating Patients With Myelofibrosis and Myeloid Metaplasia
RATIONALE: Tipifarnib may stop the growth of tumor cells by blocking the enzymes necessary for tumor cell growth. PURPOSE: Phase II trial to study the effectiveness of tipifarnib in treating patients who have myelofibrosis with myeloidmetaplasia. Condition: – chronic idiopathic myelofibrosis – Polycythemia Vera – Essential Thrombocythemia…
Blood
01 Jan 2013
Induction of Stable Chimerism for Sickle Cell Anemia
To investigate a modified hematopoeitic cell transplantation (HCT) procedure for sickle cell disease that significantly reduces the toxicity of HCT, yet retains its therapeutic benefit. To investigate a modified hematopoeitic cell transplantation (HCT) procedure for sickle cell disease that significantly reduces the toxicity of HCT, yet retains its therapeutic benefit.
Blood
01 Jan 2013
BEAM Trial
Purpose As many more premature infants survive, the numbers of these infants with health problems also has increased. The rate of cerebral palsy in extremely premature infants is approximately 20%. Magnesium sulfate, the most commonly used drug in the US used to stop premature labor may prevent CP. This…
Blood
01 Jan 2013
Aggressive vs. conservative red blood cell transfusion therapy in surgical patients with Cardiovascular Disease
Purpose: To compare aggressive with conservative red blood cell transfusion therapy in surgical patients with cardiovascular disease. Official Title Conditions – Anemia- Blood Disease- Blood Transfusion- Cardiovascular Diseases- Heart Diseases- Myocardial Infarction- Thromboembolism- Pneumonia- Cerebrovascular Accident Study Type Interventional Study Design Preventional, Randomised. Further Details BACKGROUND: Red blood cell…
Blood
21 Dec 2012
Intensified chemotherapy shows promise for children with very high-risk form of leukaemia
Young patients with an aggressive form of leukaemia who are likely to relapse after chemotherapy treatment can significantly reduce those odds by receiving additional courses of chemotherapy, suggest the findings of a clinical trial led by investigators at Dana-Farber/Children’s Hospital Cancer Center in Boston. The trial leaders will present the…
Blood
14 Dec 2012
New research shows an interesting twist in the fight against malaria
New research published in the prestigious Science journal has challenged previous notions about how the body fights against malaria infection. Scientists have discovered that platelets, normally known for their role in preventing bleeding, can actually target and kill the parasite that causes malaria as it grows inside red blood cells.
Blood
12 Dec 2012
Babies get a better chance to escape a dangerous health cycle
A promising step forward in stopping an intergenerational cycle of birth complications, diabetes and obesity associated with gestational diabetes has been made by researchers at the University of Sydney. “To our knowledge, this is the first study to show that mums with carefully controlled gestational diabetes mellitus (GDM) can give…
Blood
03 Dec 2012
Better blood transfusions for preterm babies
Results of new research from the University of Adelaide are a promising step forward in helping to improve the quality of life-saving blood transfusions for preterm babies, by reducing the likelihood of adverse inflammatory responses to the blood. Blood transfusions are among the most common medical procedures experienced by preterm…
Blood
23 Apr 2012
Diabetic retinopathy
Diabetic retinopathy is the most common of all diabetic eye diseases and typically affects both eyes. It is a severe condition which may cause vision…
