Cancer
01 Jan 2013
Effect of Dietary, Lifestyle, and Environmental Factors on Patients With Early-Stage Bladder Cancer
Rationale: Learning about the long-term effects of dietary, lifestyle, and environmental factors on the risk of cancer progression and recurrence may help the study of bladder cancer in the future.Purpose: This clinical trial is studying how dietary, lifestyle, and environmental factors affect patients with early-stage bladder cancer.
Official TitleBladder Cancer Prognosis Programme (Incorporating SELENIB Trial).
Cancer
01 Jan 2013
Trial of Adjuvant Chemotherapy for Gastric Cancer
This study is designed to evaluate the efficacy of the intraperitoneal chemotherapy with early mitomycin administration and adding cisplatin to prolonged treatment with doxifluridine compared to mitomycin plus doxifluridine in resected advanced gastric cancer. Official Title A Phase III Randomised Controlled Trial of Adjuvant Chemotherapy for Gastric Adenocarcinoma: Mitomycin and…
Cancer
01 Jan 2013
Temozolomide With or Without Radiation Therapy to the Brain in Treating Patients With Stage IV Melanoma That is Metastatic to the Brain
Rationale: Drugs used in chemotherapy use different ways to stop tumour cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumour cells. It is not yet known if chemotherapy is more effective with or without radiation therapy in treating brain metastases.Purpose: Randomised phase…
Bone
01 Jan 2013
Music in Reducing Anxiety and Pain in Adult Patients Undergoing Bone Marrow Biopsy for Haematologic Cancers or Other Diseases
Rationale:Listening to relaxing music during a bone marrow biopsy may be effective in reducing anxiety and pain.Purpose:This randomised clinical trial is studying how well music works in reducing anxiety and pain in adult patients undergoing bone marrow biopsy for haematologic cancers or other diseases. Official Title Use of Music to…
Blood
01 Jan 2013
GM-CSF Vaccinations After Allogeneic Blood Stem Cell Transplantation in Patients With Advanced Myeloid Malignancies
The purpose of this study is to investigate whether the addition of a vaccine after participants reduced intensity transplant will be safe and beneficial. The vaccine used in this trial, called GVAX, will be made from the participants own leukaemia cells, and will be given between 1-4 months after transplant.
Blood
01 Jan 2013
Study to Determine the Effect and Safety of an Oral Janus Kinase 2 (JAK2)-Inhibitor in Patients with Multiple Myeloma
The purpose of this study is to determine clinical efficacy and safety of INCB018424, a small molecule Janus kinase (JAK) inhibitor, in patients with refractory or relapsed multiple myeloma. Official Title A Phase 2, Two Stage, Open-Label, Clinical Trial to Determine the Therapeutic Effect and Safety of an Oral JAK2-Inhibitor…
Blood
01 Jan 2013
Pesticides in the Households of Healthy Volunteers and Young Patients With Leukaemia
Rationale: Learning about pesticides in the households of young patients with leukaemia and in the households of healthy volunteers may help scientists better understand the risk of leukaemia.Purpose: This epidemiology study is identifying environmental factors related to the risk of leukaemia in the households of healthy volunteers and in the…
Cancer
01 Jan 2013
Subcutaneous Treatment With Icatibant for Acute Attacks of Hereditary Angioedema
The purpose of this study is to assess the efficacy and safety of Icatibant, a bradykinin antagonist in the treatment of acute cutaneous and/or abdominal attacks in patients with hereditary angioedema (HAE). Official Title Randomised, Double Blind, Placebo-Controlled, Multicenter Study of a Subcutaneous Formulation of Icatibant for the Treatment of…
Cancer
01 Jan 2013
Intralesional PV-10 Chemoablation of Metastatic Melanoma
The objective of this study is to investigate the safety of intralesional (IL) PV-10 for the treatment of metastatic melanoma. This study will also include a preliminary assessment of response of treated and untreated lesions by clinical evaluation at follow-up of 12 to 24 weeks following IL PV-10 treatment. Official…
