Cancer
02 Aug 2013
Missing piece of paediatric cancer puzzle found
Most of the time, it takes decades of accumulating genetic errors for a tumor to develop. While this explains the general occurrence of cancer in adults, it leaves a gap in understanding of the cause of pediatric tumors. In a study published in the July issue of the Proceedings of the…
Blood
27 Apr 2013
Lymphatic System
The lymphatic system the body's secondary circulatory system. Its functions are closely linked to the functions of the body's primary circulatory system, the blood circulation. Organs and cells of the lymphatic system play an integral role in supporting the immune system, which is a functional system consisting of cells (e.g. blood cells which fight infection) and molecules (e.g. antibodies which protect against particular diseases). Unlike other body systems the immune system has no organs.
Cancer
01 Mar 2013
Reducing tumour growth and spread of advanced neuroblastoma
In a world-first discovery, researchers at Children’s Cancer Institute Australia (CCIA) have found a potential new way to reduce neuroblastoma tumour growth and metastasis. The findings, which have been published in Oncogene, may lead to the development of more targeted treatments for neuroblastoma and potentially save the lives of more…
Cancer
01 Jan 2013
The Safety Evaluation of the GSK-580299 Vaccine in Women from the Control Group in the Primary NCT00294047 Study
This extension study is designed to assess the safety of GSK Biological’s HPV vaccine GSK580299 in female subjects who took part in the primary study NCT00294047 and received the control vaccine in countries for which the licensed GSK HPV vaccine is not indicated for the subject’s age group (26 years…
Cancer
01 Jan 2013
Phase 3 Study of Immunotherapy to Treat Advanced Prostate Cancer
The purpose of this study is to determine if patients with metastatic prostate cancer who have not received chemotherapy live longer when treated with ipilimumab than those treated with a placebo. Official Title Randomized, Double-Blind, Phase 3 Trial to Compare the Efficacy of Ipilimumab vs Placebo in Asymptomatic or Minimally…
Cancer
01 Jan 2013
Nexavar-Tarceva Combination Therapy for First Line Treatment of Patients Diagnosed With Hepatocellular Carcinoma
This is a randomised trial to evaluate the clinical benefit of sorafenib and erlotinib versus sorafenib and placebo in subjects with unresectable advanced or metastatic Child-Pugh A…
Cancer
01 Jan 2013
A Study of Avastin (Bevacizumab) in Combination With Temozolomide and Radiotherapy in Patients With Newly Diagnosed Glioblastoma
This two-arm study will investigate the efficacy and safety of the addition of bevacizumab (Avastin) to the current standard of care (multimodality therapy of concurrent radiotherapy plus temozolomide followed by adjuvant temozolomide) as compared to the current standard of care alone. Patients will be randomly assigned to either the Avastin…
Cancer
01 Jan 2013
CyberKnife Radiosurgery for Organ-Confined Prostate Cancer: Homogenous Dose Distribution
The purpose of this study is to determine the effects of CyberKnife radiosurgery in patients with early stage organ-confined prostate cancer. Official Title Prospective Evaluation of CyberKnife Stereotactic Radiosurgery for Low and Intermediate Risk Prostate Cancer: Homogenous Dose Distribution. Conditions Prostate Cancer Prostatic Cancer Prostate Neoplasms…
Cancer
01 Jan 2013
Diagnostic Study of Patients With Stage I Testicular Cancer
Rationale: Diagnostic procedures may improve a doctor’s ability to predict the recurrence of testicular cancer.Purpose: Diagnostic trial to detect the risk of recurrent disease in patients who have stage I testicular cancer and who have undergone orchiectomy within the previous 12 weeks. Official Title Correlation of Histopathology, Immunohistochemistry and Quantitative…
