Oncology

Cancer 01 Jan 2013

Chemotherapy Plus Radiation Therapy in Treating Patients With Stage II or Stage III Anal Cancer

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug or combining radiation therapy with chemotherapy may kill more tumor cells. It is not yet known whether fluorouracil and mitomycin plus radiation therapy is more…
Cancer 01 Jan 2013

Open label study of ONTAK (denileukin diftitox) in previously treated Cutaneous T-cell Lymphoma patients.

The purpose of this study is to provide an opportunity for patients who exhibit progressive disease while receiving placebo on the companion 93-04-11 study to receive ONTAK. It is also designed to determine the effectiveness of ONTAK in CTCL patients whose tumors do not express CD25. Official Title A multicenter…
Cancer 01 Jan 2013

Genetic Study of Young Patients With Colorectal Cancer

RATIONALE: Identifying genemutations (microsatellite instability) may allow doctors to plan effective treatment for patients who develop colorectal cancer at an early age. Official Title Genetic Study of the Prognostic Significance of Microsatellite Instability in Patients With Early Age-of-Onset Stage I-III Colorectal Cancer Conditions – Colon Cancer- hereditary non-polyposis colon…
Cancer 01 Jan 2013

Lycopene in Treating Patients With Metastatic Prostate Cancer

RATIONALE: Lycopene, a substance found in tomatoes, may lower prostate-specific antigen (PSA) levels and slow or prevent the development of prostate cancer. RATIONALE: Lycopene, a substance found in tomatoes, may lower prostate-specific antigen (PSA) levels and slow or prevent the development of prostate cancer. PURPOSE: Phase II trial to study…
Cancer 01 Jan 2013

Tumor Vaccine and Interferon gamma in Treating Patients With Refractory Epithelial Ovarian Cancer

RATIONALE: Vaccines made from a person’s cancer cells may make the body build an immune response to and kill their tumor cells. Combining vaccine therapy with interferon gamma may be a more effective treatment for epithelial ovarian cancer. RATIONALE: Vaccines made from a person’s cancer cells may make the body…
Cancer 01 Jan 2013

Low-Fat Diet and/or Flaxseed in Preventing Prostate Cancer

RATIONALE: A diet that is low in fat and/or high in flaxseed may slow or prevent disease progression of prostate cancer. RATIONALE: A diet that is low in fat and/or high in flaxseed may slow or prevent disease progression of prostate cancer.PURPOSE: Randomizedphase II trial to study the effectiveness of…
Cancer 01 Jan 2013

Combination Chemotherapy in Treating Patients With Liver Metastases from Colorectal Cancer

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells. It is not yet known which chemotherapy regimen is more effective for metastatic colorectal cancer. PURPOSE: Randomizedphase III trial…
Cancer 01 Jan 2013

Imiquimod in Preventing Cervical Cancer in Women With Cervical Neoplasia

RATIONALE: Chemoprevention therapy is the use of certain substances to try to prevent the development of cancer. Applying topicalimiquimod before abnormal cervical cells are removed may be effective in preventing cervical cancer. RATIONALE: Chemoprevention therapy is the use of certain substances to try to prevent the development of cancer. Applying…
Cancer 01 Jan 2013

Fruit and Vegetable Extracts in Treating Patients With Stage I, Stage II, or Stage III Head and Neck Cancer

RATIONALE: Chemoprevention therapy is the use of certain substances to try to prevent the development or recurrence of cancer. Fruit and vegetable extracts may be effective in preventing the recurrence or further development of head and neck cancer. RATIONALE: Chemoprevention therapy is the use of certain substances to try to…