Cancer
01 Jan 2013
A Dose-Escalation Vaccine Trial In HER2-Overexpressing Patients With High-Risk Breast Cancer
This trial will test how safe this vaccine is. It also tests whether its introduction induces an immune response by stimulating the patient’s own immune system to recognize a specific target molecule called HER2, which is overexpressed in many breast cancers. This trial will test how safe this vaccine is.
Cancer
01 Jan 2013
Bexarotene in Preventing Breast Cancer in Women at Genetic Risk
RATIONALE: Chemoprevention therapy uses certain drugs to try to prevent the development or recurrence of cancer. It is not yet known whether bexarotene is effective in preventing breast cancer. Official Title Randomized Chemoprevention Study of Bexarotene in Women at High Genetic Risk for Breast Cancer Conditions – Breast Cancer Study…
Cancer
01 Jan 2013
Screening Tests in Detecting Colorectal Cancer
RATIONALE: Screening tests may help doctors detect cancer cells early and plan more effective treatment for colorectal cancer. Official Title Randomized Screening Study of Fecal Occult Blood Testing and Multitarget DNA-Based Assay Panel Testing Followed By Colonoscopy in the Detection of Colorectal Cancer Conditions – Colon Cancer- Rectal Cancer Study…
Cancer
01 Jan 2013
Celecoxib in Preventing Breast Cancer in At-Risk Premenopausal Women
RATIONALE: Chemoprevention therapy uses certain drugs to try to prevent the development or recurrence of cancer. Celecoxib may be effective in preventing breast cancer in at-risk women. Official Title Phase II Chemoprevention Study of Celecoxib in Premenopausal Women at High Risk For Estrogen Receptor-Negative Breast Cancer Conditions -Breast Cancer Study…
Cancer
01 Jan 2013
Trial for First-Line Treatment of Colorectal Cancer
In this study, patients will receive either ALIMTA (pemetrexed) plus irinotecan or 5-fluorouracil (5-FU), leucovorin, and irinotecan. The purposes of this study are to determine: How ALIMTA plus irinotecan compares with 5-FU, leucovorin, and irinotecan in terms of efficacy. The safety of ALIMTA plus irinotecan and any side…
Cancer
01 Jan 2013
Vaccine Treatment for Advanced Melanoma
This study will examine the safety and effectiveness of treatment with an experimental vaccine for melanoma, a type of cancer that arises from pigmented areas, usually of the skin. Melanoma tumors produce a protein called gp100. Vaccination with this protein may boost the immune system’s fight against the cancer. The…
Cancer
01 Jan 2013
Exemestane Compared With Anastrozole, With or Without Celecoxib, in Treating Postmenopausal Women After Surgery for Primary Breast Cancer
RATIONALE: Estrogen can stimulate the growth of breast cancer cells. Hormone therapy using exemestane or anastrozole may fight breast cancer by reducing the production of estrogen. It is not yet known whether exemestane is more effective than anastrozole, with or without celecoxib, in preventing the recurrence of breast cancer. RATIONALE:…
Cancer
01 Jan 2013
Risedronate Sodium on Bone in Postmenopausal Women with Hormone-Receptor-Positive Early Breast Cancer
The purpose of this study is to evaluate safety parameters of anastrozole with regard to its potential effects on postmenopausal bone loss and on lipid profiles. This trial is conducted to investigate the effects of risedronate on BMD and on bone metabolism in postmenopausal women using anastrozole as adjuvant therapy…
Cancer
01 Jan 2013
Adjuvant Tamoxifen Compared With Anastrozole in Treating Postmenopausal Women With Ductal Carcinoma In Situ
RATIONALE: Estrogen can stimulate the growth of breast cancer cells. Hormone therapy using either tamoxifen or anastrozole may fight breast cancer by blocking the uptake of estrogen. It is not yet known whether tamoxifen is more effective than anastrozole in preventing breast cancer after surgery for ductal carcinoma in situ.
