Oncology

Cancer 01 Jan 2013

Trial of PI-88 with Docetaxel in Advanced Non-Small-Cell Lung Cancer (NSCLC)

PI-88 is a new experimental drug that inhibits tumour growth by reducing the formation of new blood vessels into tumours. Docetaxel is a standard second-line treatment offered to patients with non-small-cell lung cancer who haven’t responded to first-line therapies (platinum-based drugs or radiotherapy). Of this group of patients, only 20%…
Cancer 01 Jan 2013

Gemzar Prolongs Survival in Breast Cancer Trial

Eli Lilly and Co’s drug Gemzar should be more widely used to treat advanced breast cancer following a trial in which people taking it and the standard drug paclitaxel lived months longer than those taking paclitaxel alone, a researcher said on Saturday. Official Title Conditions Study Type Study Design Further…
Cancer 01 Jan 2013

The role of gemcitabine in the management of women with locally advanced and metastatic breast cancer

Prof Michael Friedlander Department of Medicine, Prince of Wales Clinical School, Randwick, NSW Cytotoxic chemotherapy plays an important role in the treatment of women with hormone-refractory or hormone-insensitive breast cancer. These agents have demonstrated benefits in providing symptom relief, temporarily reversing or delaying disease progression, and prolonging life1 with…
Cancer 01 Jan 2013

MabThera in aggressive non-Hodgkin’s lymphoma

Study of MabThera in aggressive non-Hodgkin’s lymphoma in patients less than 60 years old halted two years early due to significant efficacy benefits Official Title Conditions Study Type Study Design Further Details Study Start Eligibility & Criteria Total Enrolment Contact Details…
Cancer 01 Jan 2013

Breast Cancer – HER2 Testing Recommendations in Australia

The following is an abstract taken from Taylor and Francis Health Sciences, discussing HER2 testing recommendations in Australia. Official Title Conditions Study Type Study Design Further Details Study Start Eligibility & Criteria Total Enrolment Contact Details…
Cancer 01 Jan 2013

Vaccine Therapy in Treating Patients With Cancer of the Gastrointestinal Tract

Vaccines may make the body build an immune response to kill tumor cells. Vaccines may make the body build an immune response to kill tumor cells.Randomizedphase II trial to compare the effectiveness of two different vaccines in treating patients who have cancer of the gastrointestinal tract. Condition:- Gastrointestinal CancerStudy Type:…
Bone 01 Jan 2013

Combination Chemotherapy and Peripheral Stem Cell Transplantation With or Without Radiation Therapy and/or Surgery in Treating Patients With Ewing’s Sarcoma

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Peripheral stem cell transplantation may allow the doctor to give higher doses of chemotherapy and kill more tumor cells. It is…
Cancer 01 Jan 2013

Bevacizumab to Treat Inflammatory Breast Cancer

This study will evaluate the effectiveness of the drug bevacizumab, in combination with doxorubicin and docetaxel, in improving survival of patients with inflammatory breast cancer. This aggressive breast cancer, which often causes a red, swollen, tender breast, is associated with a poor prognosis. Bevacizumab blocks the growth of new blood…
Cancer 01 Jan 2013

GW572016 For Treatment Of Refractory Metastatic Breast Cancer

The purpose of this study is to determine the efficacy of an oral dual kinase inhibitor for the treatment of metastatic breast cancer tumors that are known to overexpress ErbB2 in a refractory patient population. Official Title Conditions – Metastatic breast cancer Study Type Interventional Study Design Treatment, Non-Randomized, Open…