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Migraine and Healthy Eyes Research Project
Chronic Pain 01 Jan 2013

Migraine and Healthy Eyes Research Project

Volunteers are invited to participate in a research study assessing the effects of migraine headaches on visual function (HREC#0932638). The study will involve up to three test sessions, each of which may take up to three hours. During the sessions, the following will be performed:An eye examination to determine whether you are eligible to…
Optical Coherence Tomography Assessment of Intimal Tissue and Malapposition (OPTIMA)
Research and Trials 01 Jan 2013

Optical Coherence Tomography Assessment of Intimal Tissue and Malapposition (OPTIMA)

The purpose of this study is to use a high-resolution intracoronary imaging modality, called optical coherence tomography (OCT) to examine two different types of coronary artery stents used to treat patients with coronary artery disease. Official Title Optical Coherence Tomography Assessment of Intimal Tissue and Malapposition: A Randomized Comparison of…
Phase 3 Study of Immunotherapy to Treat Advanced Prostate Cancer
Cancer 01 Jan 2013

Phase 3 Study of Immunotherapy to Treat Advanced Prostate Cancer

The purpose of this study is to determine if patients with metastatic prostate cancer who have not received chemotherapy live longer when treated with ipilimumab than those treated with a placebo. Official Title Randomized, Double-Blind, Phase 3 Trial to Compare the Efficacy of Ipilimumab vs Placebo in Asymptomatic or Minimally…
Seizure Advisory System Feasibility Study
Research and Trials 01 Jan 2013

Seizure Advisory System Feasibility Study

The purpose of this prospective, single-arm, unblinded, multicenter clinical study is to evaluate the safety and effectiveness of the NeuroVista Seizure Advisory System (SAS) in patients with medically refractory epilepsy. A total of 10 subjects will be implanted at up to three study sites. Official Title Safety and Effectiveness of…
Dose-Finding Study of Favipiravir in the Treatment of Uncomplicated Influenza
Research and Trials 01 Jan 2013

Dose-Finding Study of Favipiravir in the Treatment of Uncomplicated Influenza

This is a Phase 2, randomized, double-blind, placebo-controlled multicenter study evaluating the efficacy and safety of two doses of favipiravir in older adult patients with uncomplicated influenza. Official Title A Phase 2, Randomized, Double-Blind, Placebo-Controlled Multicenter Study Evaluating the Efficacy and Safety of Two Doses of Favipiravir in Older Adult…
Safety and Efficacy of GS-9350-boosted Atazanavir Versus Ritonavir-boosted Atazanavir in HIV-1 Infected Adults
Research and Trials 01 Jan 2013

Safety and Efficacy of GS-9350-boosted Atazanavir Versus Ritonavir-boosted Atazanavir in HIV-1 Infected Adults

To evaluate the safety and efficacy of a regimen containing GS-9350-boosted atazanavir plus emtricitabine/tenofovir disoproxil fumarate versus ritonavir-boosted atazanavir plus emtricitabine/tenofovir disoproxil fumarate in HIV 1 infected, antiretroviral treatment-naïve adults. Development of GS-9350 as a "pharmacoenhancer" could provide a beneficial alternative to ritonavir for use in combination with protease inhibitors.
Australasian Resuscitation In Sepsis Evaluation Randomised Controlled Trial (ARISE)
Research and Trials 01 Jan 2013

Australasian Resuscitation In Sepsis Evaluation Randomised Controlled Trial (ARISE)

EGDT, compared to standard Australasian resuscitation practice, reduces 90-day all-cause mortality in patients presenting to the ED with severe sepsis.
Radiotherapy for Neurotropic Melanoma of the Head and Neck (RTN2)
Cancer 01 Jan 2013

Radiotherapy for Neurotropic Melanoma of the Head and Neck (RTN2)

Melanoma is a serious and common malignancy in Australia. It is the third most common cancer in Australia and approximately 1000 Australians will die of…
Randomised, Placebo-Controlled Study to Evaluate Safety and Effectiveness of Ambrisentan in IPF (ARTEMIS)
Lungs 01 Jan 2013

Randomised, Placebo-Controlled Study to Evaluate Safety and Effectiveness of Ambrisentan in IPF (ARTEMIS)

The ARTEMIS-IPF study is for people who have been diagnosed with IPF and are between 40 and 80 years of age. People who have been…