Neurology
01 Jan 2013
Evaluation of Long-Term Safety and Efficacy of Pregabalin in Patients With Partial Seizures.
To determine long-term safety and efficacy of pregabalin in patients with partial seizures. Official Title Pregabalin Open-Label Add-On Trial: An Open-Label, Multicenter Follow-On Study to Determine Long-Term Safety and Efficacy in Patients With Partial Seizures. Conditions Seizure Disorder, Partial Study Type Interventional Study Design Treatment, Non-Randomized, Open Label,…
Neurology
01 Jan 2013
Efficacy and Safety of Fingolimod in Patients With Relapsing-Remitting Multiple Sclerosis With Optional Extension Phase (TRANSFORMS)
This study will assess safety, tolerability and efficacy of two doses of oral fingolimod versus interferon Beta-1a to reduce the frequency of relapses in patients with relapsing-remitting multiple sclerosis. Official Title A 12-Month Study Comparing the Efficacy and Safety of Two Doses of Fingolimod Versus Interferon Beta-1a in Patients With…
Research and Trials
01 Jan 2013
The Neurobiology of Depressive Illness
We aim to determine why patients with depression are at an elevated risk for the development of coronary heart disease, and resolve whether the severity of a patient’s depression has a counterpart in demonstrable abnormalities in brain chemistry. Official Title The Neurobiology of Depressive Illness: Causes and Consequences of Altered…
Mental Health
01 Jan 2013
The Use of Selective Estrogen Receptor Modulators in the Treatment of Schizophrenia- a Pilot Study
The aim of the project is to investigate the use of raloxifene (a new form of estrogen) as a treatment for schizophrenia in postmenopausal women. Official Title The Use of Selective Estrogen Receptor Modulators in the Treatment of Schizophrenia- a Pilot Study Conditions Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorder Study Type…
Mental Health
01 Jan 2013
A Study of Risperidone Long-Acting Injection Versus Oral Antipsychotics in Schizophrenia Patients With a History of Being Poorly Compliant With Taking Their Medication
The purpose of this study is to evaluate risperidone long-acting injection (an antipsychotic medication) versus oral antipsychotics in schizophrenia patients with a history of being poorly compliant with taking their medication. Official Title Pragmatic Randomized Trial of ‘Risperdal CONSTA’ (Risperidone) Versus Oral Atypical Antipsychotics in Poorly Adherent Subjects With Schizophrenia…
Research and Trials
01 Jan 2013
Effect of the ‘Mother and Baby’ Program on Well-Being
The study investigates the effect of the ‘Mother and Baby’ (M&B) program on the psychological health and well-being of new mothers 6-10 weeks following the birth of their baby. The M&B program is an 8-week program of group exercise and education sessions provided by various health professionals. The design of…
Mental Health
01 Jan 2013
Treatment of Comorbid Depression and Substance Abuse in Young People
This study aims to treat young people with an adjunctive integrated Cognitive Behaviour Therapy (CBT) intervention and to examine the acceptability of this treatment approach within this population. The study will also include a pilot placebo-controlled trial of sertraline for those young people who fail to or only partially respond…
Mental Health
01 Jan 2013
Trial for the Treatment of Alcohol Dependence
The purpose of this study is to compare the effectiveness of two anti-craving medications, naltrexone versus acamprosate, in the treatment of alcohol dependence. Official Title The Role of Pharmacotherapy in Prevention of Relapse in Alcohol Dependence Conditions Alcoholism Study Type Interventional Study Design Treatment, Randomized, Double-Blind, Placebo Control, Parallel Assignment,…
Mental Health
01 Jan 2013
An Open-Label Extension Study Of Lamotrigine In Subjects With Bipolar Disorder
The precursor study (SCA101469) was an open-label, prospective multicentre study in adult subjects diagnosed with bipolar disorder consisting of 36 weeks treatment with lamotrigine. The current study is to provide 12 months post study access to open-label lamotrigine for participants of the SCA101469 study. Official Title An Open-Label Extension Study…
