Heart
01 Jan 2013
Fondaparinux Use in a Broad Range of Patients with ST-segment Elevation Acute Myocardial Infarction (MI)
The purpose of this research study is to determine the efficacy and safety of fondaparinux (Arixtra) in preventing death and repeat heart attacks and their complications. Official Title Safety and efficacy trial evaluating fondaparinux use in a broad range of patients with ST segment elevation acute MI Conditions – Myocardial…
Cancer
01 Jan 2013
A Dose-Escalation Vaccine Trial In HER2-Overexpressing Patients With High-Risk Breast Cancer
This trial will test how safe this vaccine is. It also tests whether its introduction induces an immune response by stimulating the patient’s own immune system to recognize a specific target molecule called HER2, which is overexpressed in many breast cancers. This trial will test how safe this vaccine is.
Heart
01 Jan 2013
A safety and efficacy trial evaluating the use of SanOrg34006 compared to warfarin or acenocoumarol in patients with atrial fibrillation
This trial will include patients who have a heart condition called atrial fibrillation. Atrial fibrillation is an abnormal rhythm (irregular beat) in the heart. Patients with atrial fibrillation have an increased chance for a blood clot to form in the heart and move to other blood vessels in the body…
Heart
01 Jan 2013
Gender, Obesity, C-Reactive Protein, and Oxidative Stress
This randomized placebo-controlled trial will test whether supplementing with vitamins C and E can lower markers of inflammation and oxidative stress in healthy adults. We will examine whether one antioxidant vitamin is more effective than another, and whether gender or body fat influence the treatment effects. We will also determine…
Heart
01 Jan 2013
Qigong Therapy For Heart Device Patients
The goal of this study is to improve the overall physical health and quality of life of patients attached to mechanical heart devices while awaiting heart transplantation. Qigong, an ancient Chinese exercise that involves active participation of the individual in the form of meditation, breathing exercises and simple physical movements,…
Heart
01 Jan 2013
Open Study of enoxaparin vs. unfractionated heparin in patients with acute coronary syndromes
Patients experiencing a mild heart attack will receive one of two medications which thin the blood to discern which is superior. Official Title A Prospective, Randomized, Open-label, Multicenter Study in Patients Presenting with Acute Coronary Syndromes (ACS) Conditions – Unstable Angina- Myocardial Infarction- Myocardial Ischemia Study Type Interventional Study…
Heart
01 Jan 2013
Study of Heart Transplant Rejection
This study will investigate the causes of acute and chronic rejection of transplanted hearts. To find better ways to detect, treat and possibly prevent heart transplant rejection, more information about the cause is needed. Acute and chronic heart transplant rejection may be caused by certain substances the body produces in…
Heart
01 Jan 2013
Estrogen, Cytokines and Heart Failure in Women
To determine the effects of estrogen therapy on postmenopausal women with congestive heart failure. Official Title Conditions – Cardiovascular Diseases- Heart Failure, Congestive- Heart Diseases- Menopause Study Type Interventional Study Design Randomized, Double-Blind, Placebo Control Further Details BACKGROUND: Congestive heart failure (CHF) is a leading cause of morbidity,…
Heart
01 Jan 2013
Outcomes following myocardial revascularization: on and off cardiopulmonary bypass
Ischemic heart disease is one of the most frequent diagnoses in the VA system. Moreover, 5,819 coronary artery bypass graft (CABG-only) procedures were performed in the VA in FY 1999. Throughout VA and non-VA cardiac surgery programs nationwide, myocardial revascularization is now being performed using two surgical techniques. One technique…
