Heart
01 Jan 2013
Periodontitis and Cardiovascular Events or
The purpose of this study is to determine if treating periodontal infections (gum problems) will lead to fewer heart problems in patients at high risk for cardiovascular disease. Official Title Periodontal Intervention for Cardiac Events: A Pilot Trial Conditions – Cardiovascular Disease- Coronary Heart Disease- Myocardial Infarction- Cerebrovascular Accident…
Heart
01 Jan 2013
EVEREST: Efficacy of Vasopressin antagonism in hEart failuRE: outcome Study with Tolvaptan
The purpose of this study is to compare the effectiveness of tolvaptan or placebo in adults with worsening congestive heart failure (CHF). The purpose of this study is to compare the effectiveness of tolvaptan or placebo in adults with worsening congestive heart failure (CHF). Condition: – Congestive Heart FailureStudy Type:…
Heart
01 Jan 2013
WARCEF (Warfarin versus Aspirin in Reduced Cardiac Ejection Fraction)
The purpose of this study is to determine which of two treatments, Warfarin or aspirin, is better for preventing death and stroke in patients with poor heart function. The purpose of this study is to determine which of two treatments, Warfarin or aspirin, is better for preventing death and stroke…
Heart
01 Jan 2013
ARISE (Aggressive Reduction of Inflammation Stops Events)
To assess the safety and efficacy of AGI-1067, as compared to placebo, in the treatment of vascular inflammation and atherosclerosis by assessing the reduction in cardiovascular events. To assess the safety and efficacy of AGI-1067, as compared to placebo, in the treatment of vascular inflammation and atherosclerosis by assessing the…
Heart
01 Jan 2013
BARI 2D
The BARI 2D (Bypass Angioplasty Revascularization Investigation in Type 2 Diabetics) trial is a multicenter study that uses a 2×2 factorial design, with 2800 patients being assigned at random to initial elective revascularization with aggressive medical therapy or aggressive medical therapy alone with equal probability, and simultaneously being assigned at…
Bone
01 Jan 2013
Look AHEAD
Purpose The Look AHEAD study is a multicenter, randomized clinical trial to examine the long-term effects of a lifestyle intervention designed to achieve and maintain weight loss. The study will investigate the effects of the intervention on heart attacks, stroke and cardiovascular-related death in individuals with type 2 diabetes…
Heart
01 Jan 2013
Clinical Trial of Dietary Protein on Blood Pressure
Purpose To examine the effect of dietary protein supplementation on blood pressure. Official Title Conditions – Cardiovascular Diseases- Hypertension- Heart Diseases Study Type Interventional Study Design Prevention, Randomized, Double-Blind, Crossover Assignment Further Details BACKGROUND: At least 50 million adult Americans have hypertension, one of the most important modifiable…
Blood
01 Jan 2013
Aggressive vs. conservative red blood cell transfusion therapy in surgical patients with Cardiovascular Disease
Purpose: To compare aggressive with conservative red blood cell transfusion therapy in surgical patients with cardiovascular disease. Official Title Conditions – Anemia- Blood Disease- Blood Transfusion- Cardiovascular Diseases- Heart Diseases- Myocardial Infarction- Thromboembolism- Pneumonia- Cerebrovascular Accident Study Type Interventional Study Design Preventional, Randomised. Further Details BACKGROUND: Red blood cell…
Heart
01 Jan 2013
Effect of B blockade on haemodynamics and brain natriuretic peptide (BNP)
The aim of the study is to test the effects of Atenolol, Pindolol and Nebivolol on central blood pressure and augmentation index. Studies of normotensive and hypertensive individuals have confirmed that pulse pressure is a better predictor of cardiovascular events than mean pressure in older adults. Official Title Conditions Study…
