Heart
01 Jan 2013
Cardiac Vulnerability in Potentially Susceptible Patients
This project is part of a program project directed toward assessing cardiac effects of particulate and other ambient air pollutants. In this project patient who have recently suffered a cardiac event are being monitored with cardiac monitors for 24 hours up to 4 times during the year following their cardiac…
Heart
01 Jan 2013
Abciximab (ReoPro) in Acute Ischemic Stroke
Multinational, Multicenter, Randomized, Double-blind, Placebo-controlled trial to evaluate efficacy and safety of Abciximab in Acute Ischemic Stroke onset within 6 hour time window and subjects who wake from sleep with stroke symptoms, and in whom the planned treatment initiation is within 3 hours of awakening. Multinational, Multicenter, Randomized, Double-blind, Placebo-controlled…
Heart
01 Jan 2013
A safety and efficacy trial evaluating the use of SanOrg34006 in the treatment of Deep Vein Thrombosis (DVT)
Patients who have deep vein thrombosis (blood clot in the leg) will be treated in this study. The purpose of the study is to compare the safety and effectiveness of a new injectible anticoagulant (blood thinning) drug administered once each week, SanOrg34006, with the standard way of treating deep vein…
Heart
01 Jan 2013
Stenting vs. Surgery to Prevent Stroke
The purpose of the Carotid Revascularization Endarterectomy versus Stenting Trial (CREST) is to compare the relatively new procedure of stent-assisted carotid angioplasty (CAS) to the traditional and accepted surgical approach of carotid endarterectomy (CEA) for the treatment of carotid artery stenosis to prevent recurrent strokes in those patients who have…
Heart
01 Jan 2013
Efficacy and Safety of Azimilide in the Prophylactic Treatment of Patients With Atrial Fibrillation
Atrial fibrillation (an abnormal rhythm in the upper chamber of the heart) is a common supraventricular arrhythmia (a type of abnormal heart rhythm) for which antiarrhythmic therapy is often prescribed. The primary goals of therapy are to maintain sinus rhythm (normal heart rhythm) and to reduce the occurrence of episodes…
Heart
01 Jan 2013
Home Automatic External Defibrillator Trial — HAT
To compare home use of an automatic external defibrillator to the local emergency medical system in survivors of a heart attack. To compare home use of an automatic external defibrillator to the local emergency medical system in survivors of a heart attack.Condition: – Cardiovascular Diseases- Myocardial Infarction- Heart Diseases- Death,…
Heart
01 Jan 2013
Oral Enoximone vs. Placebo in Advanced Chronic Heart Failure Subjects
To determine if low-dose enoximone therapy is an effective treatment for advanced chronic heart failure. Official Title ESSENTIAL Protocol No. My-021 and Protocol No. My-026, each titled: A Phase III, Randomized, Double-Blind, Multicenter, Parallel Group, Placebo-Controlled Study of Oral Enoximone vs. Placebo in Advanced Chronic Heart Failure Subjects Conditions…
Heart
01 Jan 2013
Efficacy and Safety of Azimilide in the Prophylactic Treatment of Patients With Atrial Fibrillation.
Atrial fibrillation (an abnormal rhythm in the upper chamber of the heart) is a common supraventricular arrhythmia (a type of abnormal heart rhythm) for which antiarrhythmic therapy is often prescribed. The primary goals of therapy are to maintain sinus rhythm (normal heart rhythm) and to reduce the occurrence of episodes…
Heart
01 Jan 2013
Healthy Heart Amputation Rehabilitation Treatment (H.A.R.T)
In the VA, we are achieving progress in decreasing amputation rates through early identification and multidisciplinary treatment of patients at risk for limb loss. Despite these accomplishments, however, clinical outcomes post-amputation, especially for PVD patients, have changed little because of patients’ poor cardiovascular condition complicated by the injurious consequences of…
