Research and Trials
01 Jan 2013
Short Term Effects of FX Dialysers on QOL and Inflammation
This study aims to assess the short-term effects of the FX-class Dialyser on quality of life and inflammatory markers in stable haemodialysis patients with chronic kidney failure. Official Title Short-Term Effects of the FX-Class of Haemodialyser on Quality of Life and Inflammatory Markers in Stable Dialysis Patients. Conditions Kidney Failure,…
Blood
01 Jan 2013
A Prospective, Surveillance Study to Estimate the Incidence of Pure Red Blood Cell Aplasia (Aplastic Anemia) Mediated by Erythropoietin Antibodies Among Patients With Chronic Kidney Failure and Subcutaneous Exposure to Recombinant Erythropoietin Prod
The purpose of this study is to estimate the incidence rate of pure red cell aplasia (PRCA; aplastic anemia) mediated by erythropoietin (EPO) antibodies in patients who are receiving subcutaneous (s.c.) EPREX (polysorbate 80 formulation) for the treatment of anemia associated with chronic renal failure (CRF), and to compare this…
Research and Trials
01 Jan 2013
Augmented Vs. Normal Renal Replacement Therapy in Severe Acute Renal Failure (ARF)
This study seeks to determine if increasing the dose of continuous renal replacement therapy (CRRT) reduces 90-day all cause mortality in Intensive Care Unit (ICU) patients with severe acute renal failure (ARF). Official Title Multicentre, Unblinded, Open Label, Randomised, Controlled Trial to Assess the Effect of Augmented Vs. Normal Continuous…
Cancer
01 Jan 2013
PRIME: Panitumumab Randomized Trial In Combination With Chemotherapy for Metastatic Colorectal Cancer to Determine Efficacy
The purpose of this study is to determine the treatment effect of panitumumab in combination with FOLFOX compared to FOLFOX alone as first line therapy for metatstatic colorectal cancer Official Title A Randomized, Multicenter, Phase 3 Study to Compare the Efficacy of Panitumumab in Combination With Oxaliplatin/ 5-Fluorouracil/ Leucovorin to…
Cancer
01 Jan 2013
Gemcitabine With or Without Erlotinib in Treating Patients With Unresectable Locally Advanced or Metastatic Pancreatic Cancer
Randomized phase III trial to determine the effectiveness of gemcitabine with and without erlotinib in treating patients who have unresectable locally advanced or metastatic pancreatic cancer. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Biological therapies such as erlotinib…
Bone
01 Jan 2013
A Study to Compare MPR With MP in Newly Diagnosed Multiple Myeloma Subjects 65 Years Old or Older
Phase III randomised study to compare MPR with MP in newly diagnosed Multiple Myeloma subjects who are 65 years old or older. Official Title A Phase III, Multicentre, Randomised, Double-Blind, Placebo-Controlled, 3 Arm Parallel-Group Study to Determine the Efficacy and Safety of Lenalidomide (Revlimid) in Combination With Melphalan and Prednisone…
Gastro
01 Jan 2013
Study Comparing Tigecycline Versus Ceftriaxone Sodium Plus Metronidazole in Complicated Intra-Abdominal Infection (cIAI)
This is a study of the safety and efficacy of tigecycline to ceftriaxone sodium plus metronidazole in hospitalized subjects with cIAI. Subjects will be followed for efficacy through the test-of-cure assessment. Safety evaluations will occur through the treatment and post-treatment periods and continue through resolution or stability of the adverse…
Children's health
01 Jan 2013
Hib-MenCY-TT Vaccine Study Compared to Licensed Hib and Meningococcal Serogroup C Conjugate Vaccines
This study is evaluating the safety and immunogenicity of Hib-MenCY-TT vaccine compared to control groups receiving licensed Hib or MenC conjugate vaccines, each administered at 2, 4, 6, and 12 to 15 months of age. Co-administration with live, attenuated measles, mumps, and rubella combination vaccine; and with live, attenuated varicella…
Hormones
01 Jan 2013
Contraction (Exercise) Mediated Glucose Uptake as a Therapeutic Target in Type 2 Diabetes
Diabetes Mellitus, Type 2 and Physical Activity
