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The Rabeprazole and Esomeprazole Reflux Assessment Trial (TREAT)

The primary objective of this study is to compare, the number of patients with heartburn and regurgitation symptom resolution after…

01 Jan 2013

Glycemic Load, Weight Loss and Cardiovascular Disease Risk

Glycemic Load, Weight Loss and Cardiovascular Disease Risk

To investigate the hypothesis that reducing the glycemic load of the diet will improve changes in body composition and cardio-vascular…

01 Jan 2013

Effect of Abdominal Obesity on Lipoprotein Metabolism

Effect of Abdominal Obesity on Lipoprotein Metabolism

Abdominal obesity is strongly associated with dyslipidemia, which may account for the associated increased risk of atherosclerosis and coronary disease.

01 Jan 2013

High Density Lipoprotein Turnover

High Density Lipoprotein Turnover

The objective of the study is to evaluate the effect of Rimonabant 20mg in comparison to placebo, on HDL and…

01 Jan 2013

A Randomised Trial of Preoperative Radiotherapy for Stage T3 Adenocarcinoma of Rectum

fThis is a multi-centre randomised trial comparing long course (LC) preoperative chemoradiation with short course (SC) preoperative radiotherapy for patients…

01 Jan 2013

Study of Dexlansoprazole vs Placebo on the Ability to Maintain Healing in Subjects With Healed Erosive Esophagitis.

A 6-month study to assess the ability of daily treatment with dexlansoprazole 30mg, 60 mg or placebo in maintaining healing…

01 Jan 2013

PROphylaxis for ThromboEmbolism in Critical Care Trial (PROTECT)

The purpose of this study is to evaluate the effect of Low Molecular Weight Heparin (LMWH) (dalteparin) versus Unfractionated Heparin…

01 Jan 2013

PRECISION : Prospective Randomized Evaluation of Celecoxib Integrated Safety vs Ibuprofen Or Naproxen

To answer the question of overall benefit: risk of celecoxib when compared to two most commonly prescribe traditional (non-selective) nonsteroidal…

01 Jan 2013

Blood Pressure and Glucose Lowering for the Prevention of Vascular Disease in High Risk Patients With Type 2 Diabetes.

The purpose of this study is to provide information on the risks and benefits of routine blood pressure lowering (regardless…

01 Jan 2013