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Trial of Growth Hormone Therapy in Paediatric Crohn’s Disease

The purpose of this study is to determine whether taking a growth hormone (GH) drug called somatropin causes the intestine…

01 Jan 2013

Temozolomide With or Without Radiation Therapy to the Brain in Treating Patients With Stage IV Melanoma That is Metastatic to the Brain

Rationale: Drugs used in chemotherapy use different ways to stop tumour cells from dividing so they stop growing or die.

01 Jan 2013

Comparison of Radiation Therapy Regimens in Combination With Chemotherapy in Treating Young Patients With Newly Diagnosed Standard-Risk Medulloblastoma

This randomized phase III trial is studying standard-dose radiation therapy to see how well it works compared to reduced-dose craniospinal…

01 Jan 2013

A Single Arm Trial of Oxaliplatin and 5FU With Concurrent Radiation in Patients With Metastatic Rectal Cancer

This trial is a single-arm study for patients presenting with both local and metastatic adenocarcinoma of rectum. The aims of…

01 Jan 2013

Efficacy and Safety of Colesevelam in Pediatric Patients With Genetic High Cholesterol

Efficacy and Safety of Colesevelam in Pediatric Patients With Genetic High Cholesterol

This study will evaluate the lipid-lowering effect and safety of colesevelam therapy administered to heterozygous familial pediatric patients 10 through…

01 Jan 2013

Combination Chemotherapy With or Without Peripheral Stem Cell Transplantation, Radiation Therapy, and/or Surgery in Treating Patients With Ewing’s Sarcoma

This randomized phase III trial is studying different combination chemotherapy regimens to see how well they work when given with…

01 Jan 2013

Can a Modified Fat Diet With Low Glycaemic Load Improve Insulin Sensitivity and Inflammatory Mediators in Overweight People With Chronic Heart Failure?

In overweight patients with chronic heart failure, to compare the effects of a modified fat diet with reduced glycaemic load…

01 Jan 2013

Combination Chemotherapy Plus Radiation Therapy in Treating Children With Newly Diagnosed Brain Stem Glioma

Combination Chemotherapy Plus Radiation Therapy in Treating Children With Newly Diagnosed Brain Stem Glioma

Phase I trial to study the effectiveness of vincristine plus etoposide and radiation therapy in treating children who have newly…

01 Jan 2013