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Study to Evaluate the Long-term Efficacy and Safety of Oral Tolvaptan Tablet Regimens in Subjects with Autosomal Dominant Polycystic Kidney Disease

To demonstrate whether tolvaptan modifies ADPKD progression as measured by changes from baseline (from trial 156-04-251) in total kidney volume…

01 Jan 2013

A Study in Painful Diabetic Neuropathy (COMBO-DN)

A Study in Painful Diabetic Neuropathy (COMBO-DN)

This study will investigate the efficacy of a combination treatment of duloxetine + pregabalin compared with the maximal dose of…

01 Jan 2013

The CANTATA-MSU Trial (CANagliflozin Treatment and Trial Analysis – Metformin and SUlphonylurea)

The purpose of this study is to evaluate the efficacy and safety of 2 different doses of canagliflozin compared with…

01 Jan 2013

The Stabilization of Atherosclerotic Plaque by Initiation of Darapladib Therapy Trial (STABILITY)

This study will test whether darapladib can safely lower the chances of having a cardiovascular event in people with coronary heart disease.

01 Jan 2013

The Effect of Atorvastatin on Postoperative Renal Function After Cardiac Surgery

Atorvastatin might reduce the oxidative stress that occurs during cardiopulmonary bypass, and thus, prevent or reduce the magnitude of acute kidney dysfunction in those patients…

01 Jan 2013

Audit and Screening Study to Determine the Prevalence of Peripheral Arterial Disease (ACHILLES)

Audit and Screening Study to Determine the Prevalence of Peripheral Arterial Disease (ACHILLES)

The primary objective of the study is to establish the prevalence of lower extremity peripheral arterial disease in subjects with cardiovascular disease risk factors but no…

01 Jan 2013

The PLATINUM Clinical Trial to Assess the PROMUS Element Stent System for Treatment of De Novo Coronary Artery Lesions

The PLATINUM Clinical Trial to Assess the PROMUS Element Stent System for Treatment of De Novo Coronary Artery Lesions

The purpose of this study is to evaluate the safety and effectiveness of the PROMUS ElementTM Everolimus-Eluting Coronary Stent System…

01 Jan 2013

The Study of Atherosclerosis with Ramipril and Rosiglitazone

The purpose of this study is to determine if ramipril and/or rosiglitazone retard the progression of atherosclerosis as evaluated by…

01 Jan 2013