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Using Donor Stem Cells and Alemtuzumab to Prevent Organ Rejection in Kidney Transplant Patients

Alemtuzumab is a man-made antibody used to treat certain blood disorders. This study will evaluate treatment of kidney transplant recipients…

01 Jan 2013

Trial of Adjuvant Chemotherapy for Gastric Cancer

This study is designed to evaluate the efficacy of the intraperitoneal chemotherapy with early mitomycin administration and adding cisplatin to…

01 Jan 2013

Alemtuzumab to Treat Severe Aplastic Anaemia

Alemtuzumab to Treat Severe Aplastic Anaemia

This study will evaluate the safety and usefulness of a new immunosuppressive drug, alemtuzumab (Campath®), in patients with severe aplastic…

01 Jan 2013

GM-CSF Vaccinations After Allogeneic Blood Stem Cell Transplantation in Patients With Advanced Myeloid Malignancies

The purpose of this study is to investigate whether the addition of a vaccine after participants reduced intensity transplant will…

01 Jan 2013

Study to Determine the Effect and Safety of an Oral Janus Kinase 2 (JAK2)-Inhibitor in Patients with Multiple Myeloma

The purpose of this study is to determine clinical efficacy and safety of INCB018424, a small molecule Janus kinase (JAK)…

01 Jan 2013

AZD0530 Phase II Study in Patients With Advanced Ovarian Cancer

The main purpose of this study is to determine if AZD0530 can improve the efficacy of standard chemotherapy for the…

01 Jan 2013

Bortezomib in Treating Patients With Newly Diagnosed High-Risk Stage III Multiple Myeloma

RATIONALE: Bortezomib may stop the growth of cancer cells by blocking the enzymes necessary for their growth. PURPOSE: This…

01 Jan 2013

A Randomised Trial of Preoperative Radiotherapy for Stage T3 Adenocarcinoma of Rectum

fThis is a multi-centre randomised trial comparing long course (LC) preoperative chemoradiation with short course (SC) preoperative radiotherapy for patients…

01 Jan 2013

Combination Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Children With Recurrent or Refractory Hodgkin’s or Non-Hodgkin’s Lymphoma

Phase II trial to study the effectiveness of combination chemotherapy followed by peripheral stem cell transplantation in treating children who…

01 Jan 2013