Primary hypogonadism (also referred to as testicular failure) is a condition in which a man has low levels of testosterone in his blood. In cases of primary hypogonadism, the testosterone deficiency arises because the testicles fail to produce testosterone, even though they receive signals to do so from the pituitary gland of the brain.

Hypogonadism caused by a dysfunction of the pituitary gland is called secondary or hypogonadotrophic hypogonadism. Either primary or secondary hypogonadism causes changes to a man’s body, including small testicles, lack of body hair and breast growth.

For more information, see Hypogonadism.

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