Cancer
01 Jan 2013
Combination chemotherapy of docetaxel, ifosfamide and cisplatin (DIP) in patients with metastatic urothelial cancer
The aim of this study was to evaluate the efficacy and toxicity of a new combination chemotherapy of docetaxel, ifosfamide and cisplatin (DIP) in the treatment of metastatic urothelial cancer. Official Title Combination chemotherapy of docetaxel, ifosfamide and cisplatin (DIP) in patients with metastatic urothelial cancer: a preliminary report. Conditions…
Cancer
01 Jan 2013
Study of irinotecan (CPT-11) combined with fixed dose of 5-fluorouracil (5-FU) adult patients with advanced solid tumours
Advanced solid tumors (gastrointestinal incl. Colorectal, head & neck, others) (1): to find the maximum tolerated dose (MTD) of the combined chemotherapy. (2): to determine the quantitive and qualitative toxic effects, the Dose-limiting toxicity and the recommended dose for phase II trials. (3): to define the safety profile…
Cancer
01 Jan 2013
Sulindac and Tamoxifen in Treating Patients With Desmoid Tumor
RATIONALE: Sulindac may stop the growth of cancer cells by blocking the enzymes necessary for cancer cell growth. Hormone therapy using tamoxifen may fight cancer by blocking the uptake of estrogen. Combining sulindac with tamoxifen may kill more cancer cells. PURPOSE: Phase II trial to study the effectiveness of combining…
Research and Trials
01 Jan 2013
Evaluate the Survival Benefits of Zemplar versus Calcijex in Subjects w/ Stage V Chronic Kidney Disease on Hemodialysis
To evaluate the survival benefit associated with Zemplar therapy as compared to Calcijex for the treatment of secondary hyperparathyroidism in subjects with Stage V chronic kidney disease on hemodialysis as measured by time to death. Official Title A Phase IV, Prospective, Randomized, Active-Controlled, Double-Blind, Double-Dummy, Multi-Center Study to Evaluate the…
Blood
01 Jan 2013
Safety of NXY-059 for the Treatment of Patients who have Suffered from a Stroke
This study will determine if NXY-059 is safe in patients with an acute stroke caused by bleeding in the central nervous system. Official Title CHANT (Cerebral Hemorrhage And NXY Treatment) A Double-Blind, Randomized, Placebo-Controlled, Parallel group, Multicenter, Phase IIb Study to Assess the Safety and Tolerability of Intravenous Infusion of…
Cancer
01 Jan 2013
Anti-angiogenesis Agent AG-013736 in Patients with Metastatic Melanoma
This is a Phase 2 study being conducted at multiple centers in the United States. Patients having melanoma that has spread to other parts of the body (i.e., metastatic) are eligible to participate. Patients must have disease that has been treated with no more than 1 prior treatment for metastatic…
Mental Health
01 Jan 2013
Comparison of Intramuscular Olanzapine Depot to Oral Olanzapine and Low-Dose Depot in the Maintenance Therapy of Patients With Schizophrenia
Key objectives of this clinical study are to: – Determine how well intramuscular (IM) olanzapine depot works compared to oral olanzapine – Evaluate the safety and tolerability of IM olanzapine depot compared to oral olanzapine – Evaluate different doses of IM olanzapine depot to identify the best dose(s)…
Cancer
01 Jan 2013
Study of SU011248 in Patients with Neuroendocrine Tumors
The primary objective of the study is to determine the efficacy and safety of SU011248 as a treatment for patients with advanced unresectable neuroendocrine tumor; however, CURRENTLY ONLY RECRUITING FOR PATIENTS SPECIFICALLY WITH PANCREATIC ISLET CELL TUMORS. Official Title Phase II Study of SU011248 in Patients with Neuroendocrine Tumors; however,…
Cancer
01 Jan 2013
Study of SU011248 in Patients with Metastatic Non-Small Cell Lung Cancer
The purpose of this study is to test whether SU011248 has activity and is safe in patients with metastatic non-small cell lung cancer (NSCLC) who have failed a platinum-containing regimen and docetaxel. Official Title A Phase 2 Efficacy and Safety Study of SU011248 in Patients with Metastatic Non-Small Cell Lung…
