Cancer
01 Jan 2013
RADAR Trial – Randomised Androgen Deprivation and Radiotherapy
Purpose The principal objectives of the RADAR trial is to address the hypotheses; 1) that 18 months androgen deprivation in conjunction with radiotherapy is superior to 6 months androgen deprivation prior to and during radiotherapy; 2) that 18 months Bisphosphonate therapy will prevent bone loss caused by androgen deprivation…
Cancer
01 Jan 2013
Two Chemotherapy Regimens Compared With Observation in Treating Patients With Completely Resected Pancreatic Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known which chemotherapy regimen is more effective, or whether chemotherapy is more effective than observation, in treating pancreatic cancer after surgery. PURPOSE: Phase III trial…
Cancer
01 Jan 2013
IEV and autologous peripheral blood progenitor cell transplant salvage treatment for lymphoid malignancies
Primary endpoints were to confirm the feasibility and efficacy of IEV in poor risk Hodgkin’s lymphoma and aggressive NHLs. Additional endpoints were to try to evaluate its possible role in the salvage strategy of indolent NHLs, lymphoblastic lymphoma and multiple myeloma. Analysis of toxicity and PBSC mobilization. Conclusions…
Cancer
01 Jan 2013
Head and Neck Phase III Iressa Vs Methotrexate Refractory. Iressa Vs Methotrexate (IMEX)
Purpose- This study is to compare ZD1839 (250mg and 500mg) versus methotrexate in head and neck cancer in terms of overall survival. Official Title A Phase III Randomised, Stratified, Parallel-Group, Mulit-Centre, Comparative Study of ZD1839 (Iressa) 250 mg and 500 mg Versus Methotraxate for Previously Treated Patients with Squamous Cell…
Cancer
01 Jan 2013
Brain Metastases Study
Purpose- Comparison of radiotherapy fractionation schemes for brain metastasis. Official Title To Determine Which of Two Radiotherapy Brain Fractionation Schemes is Superior in the Treatment of Brain Metastases Conditions Study Type Interventional Study Design Treatment, Randomized, Open Label, Dose Comparison, Parallel Assignment, Efficacy Study Further Details Primary Outcomes: Control of…
Cancer
01 Jan 2013
Trial in Locally Advanced and Metastatic Adrenocortical Carcinoma Treatment (FIRM-ACT)
The purpose of this study is to determine whether treatment with etoposide, doxorubicin, cisplatin and mitotane (EDP/M) prolongs survival as compared to streptozotocin and mitotane (Sz/M) in patients with advanced adrenocortical carcinoma (ACC) whose disease is not amenable to complete surgical resection. The Firm-ACT trial is the first ever conducted…
Gastro
01 Jan 2013
Probiotic and Crohn’s Disease Study
Probiotics are a food supplement containing living microorganisms, which upon ingestion in certain numbers exert health benefits beyond inherent basic nutrition. They have been shown to reduce intestinal inflammation in the inflammatory bowel diseases, Crohn’s disease (CD) and ulcerative colitis (UC). Probiotics are effective in the treatment of acute pouchitis…
Cancer
01 Jan 2013
A Feasibility Study to Evaluate Adjuvant Chemoradiotherapy for Gastric Cancer
The purpose of this study is to determine the side-effects and effectiveness of a new type of chemoradiotherapy treatment for patients who have had surgery for stomach cancer. The treatment uses epirubicin, cisplatin, and 5-fluorouracil (ECF) chemotherapy together with radiotherapy. Official Title Conditions Gastric Cancer Study Type Interventional Study Design…
Cancer
01 Jan 2013
Outcomes of Concurrent Chemo-Radiotherapy in Locally Advanced Cervical Cancer.
CCRT is considered the standard of care in LACC since 1999. However there are few reports of results of this treatment in the common practice in developing countries were this disease is most frequent. Official Title Outcomes of Concurrent Chemo-Radiotherapy (CCRT) in Locally Advanced Cervical Cancer (LACC). Results of a…
