Research and Trials
01 Jan 2013
Parathyroid Hormone (PTH) for Osteoporosis in Postmenopausal Women
Parathyroid hormone (PTH) increases bone formation and thereby improves bone density and bone strength in postmenopausal women with osteoporosis. However, prolonged PTH treatment increases bone formation less and less over time. This study will test whether increasing the daily dose of PTH sustains its ability to improve bone formation, and…
Cancer
01 Jan 2013
Effect of Fluvastatin on Biomarkers in Women Who Are Undergoing Surgery for Ductal Carcinoma In Situ or Stage I Breast Cancer
RATIONALE: Collecting samples of blood and tissue from patients with cancer to study in the laboratory may help doctors learn how fluvastatin effects biomarkers related to breast cancer.PURPOSE: This randomised phase II trial is studying how fluvastatin effects biomarkers in women undergoing surgery for ductal carcinoma in situ or stage…
Cancer
01 Jan 2013
AZD0530 Phase II Study in Patients With Advanced Ovarian Cancer
The main purpose of this study is to determine if AZD0530 can improve the efficacy of standard chemotherapy for the treatment of ovarian cancer. Official Title A Phase II, Double-Blind, Placebo-Controlled, Multi-Centre, Randomised Study of AZD0530 in Patients With Advanced Ovarian Cancer Sensitive to Platinum-Based Chemotherapy. Conditions Ovarian Neoplasms…
Research and Trials
01 Jan 2013
The ALK Grass Tablet in Subjects with Hayfever
This trial is performed to assess the efficacy and safety of the ALK Grass tablet for treatment of grass pollen induced rhinoconjunctivitis (hayfever). Official Title A Randomised, Parallel-Group, Double-Blind, Placebo-Controlled Phase III Trial Assessing the Efficacy and Safety of ALK Grass Tablet in Subjects With Seasonal Grass Pollen Induced Rhinoconjunctivitis.
Research and Trials
01 Jan 2013
ASP2151 in Subjects With Recurrent Episodes of Genital Herpes
A study of ASP2151 in subjects with recurrent outbreaks of genital herpes. Official Title A Phase II, Dose-Finding Study With ASP2151 in Subjects With Recurrent Episodes of Genital Herpes Conditions Herpes Genitalis Study Type Interventional Study Design Treatment, Randomised, Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Placebo…
Children's health
01 Jan 2013
An Effectiveness and Safety Study of ‘CONCERTA’ (Methylphenidate Hydrochloride) in the Treatment of Adolescents With Attention Deficit Hyperactivity Disorder
The purpose of this study is to evaluate the safety and effectiveness of CONCERTA (methylphenidate hydrochloride, a central nervous system (CNS) stimulant) versus placebo for the treatment of Attention Deficit Hyperactivity Disorder (ADHD) in adolescents. Official Title An Evaluation of the Safety and Effectiveness of CONCERTA (Methylphenidate Hydrochloride), up to…
Cancer
01 Jan 2013
Bortezomib in Treating Patients With Newly Diagnosed High-Risk Stage III Multiple Myeloma
RATIONALE: Bortezomib may stop the growth of cancer cells by blocking the enzymes necessary for their growth. PURPOSE: This phase II trial is studying how well bortezomib works in treating patients with newly diagnosed high-risk stage III multiple myeloma. Official Title Phase II Study Of PS-341 For Patients With…
Research and Trials
01 Jan 2013
Effect of Pantoprazole on the Symptoms of Acid Reflux Disease in Adult Patients (BY1023/M3-341)
The aim of the present study is to identify factors (such as symptom patterns and symptom scores) that influence the response to treatment with pantoprazole using different evaluation methods (e.g. ‘ReQuest’ questionnaire, patient and investigator assessment). Pantoprazole will be administered once daily in the morning at one dose level. The…
Research and Trials
01 Jan 2013
Audit of the Effect of Changing From Intravenous to Subcutaneous Administration of Erythropoeisis Stimulating Agents in Haemodialysis Patients
The purpose of this study is to audit the effects of changing all haemodialysis patients from intravenous to subcutaneous administration of ESA’s, to ensure that a cost-saving is achieved and that this does not occur at the expense of anaemia control. The dose changes will occur according to usual clinical…
