Research and Trials
01 Jan 2013
Slings and Their Effect on Skin Pressure
There are many reasons that cause skin to breakdown. This study will only compare pressure, pH and temperature with the use of slings and without the use of slings (fabricated device used to safely handle patient transfers and repositioning).There will be no difference in skin pressure, pH, or temperature with…
Heart
01 Jan 2013
Identification of Genetic Markers for Cardiopulmonary Diseases (Genotype)
This study is designed to investigate whether an association exists between certain genes/protein levels and the development of various cardiopulmonary diseases. It is hoped that this project will provide valuable insight into the understanding of these diseases. Official Title Identification of Genetic Markers for Cardiopulmonary Diseases. Conditions Cardiovascular Diseases…
Lungs
01 Jan 2013
Randomised Study of a Simple Weight Loss Program for Obese Patients With Obstructive Sleep Apnoea
The purpose of the study is to determine if weight loss interventions aimed at lifestyle modification (dietary education, food diary pedometer) result in weight loss in patients with mild-moderate obstructive sleep apnoea (OSA) when compared to usual patient care. The secondary purpose of the study is to determine if the…
Hormones
01 Jan 2013
PaTH Study: Parathyroid Hormone and Alendronate for Osteoporosis
This 2-year study will test the effectiveness of combining parathyroid hormone (PTH) and alendronate for treating osteoporosis in postmenopausal women. Alendronate is a drug used to treat osteoporosis and primarily prevents bone loss, whereas PTH increases bone formation. We will treat the study participants either with PTH and alendronate, alendronate…
Hormones
01 Jan 2013
Testosterone-Driven Growth-Hormone (GH) Secretion in Aging Men
This study is being done to understand how testosterone, the major male sex hormone, controls the pituitary gland’s secretion of growth hormone (GH). GH is an important metabolic hormone, which controls sugar; fat and protein use in the body and maintains muscle strength and bone calcium content. Both testosterone and…
Hormones
01 Jan 2013
Consequence of Lifetime Isolated Growth Hormone Deficiency
The primary goal of this proposal is to determine the consequences of life-long lack of GH on body composition, muscle strength, cardiovascular status, cardiovascular risk factors, thyroid status and bone density and metabolism, and to test which of these parameters are reversed by a 6-month course of GH replacement therapy.
Bone
01 Jan 2013
Hypovitaminosis D and an Inadequate PTH Response in Chronic Liver Disease Patients
The purpose of this study is to determine how common low levels of magnesium are in patients with end stage liver disease. In addition, investigator is trying to determine if low levels of magnesium affect the release of parathyroid hormone in patients with end stage liver disease and low vitamin…
Gastro
01 Jan 2013
Long-Term Pantoprazole Trial in Patients With Symptoms of Chronic Acid Peptic Complaints (BY1023/VMG-708)
Gastroesophageal reflux disease (GERD) is a medical condition affecting the stomach and oesophagus. GERD might occur when the lower oesophageal sphincter does not close properly and stomach contents leaks back (refluxes) into the oesophagus. GERD is one of the most common medical disorders, with estimates of up to 50% of…
Children's health
01 Jan 2013
Treatment of Children With Obstructive Sleep Apnoea and Laryngomalacia: The Role of Laser Supraglottoplasty
This is a research study of the effect of treating laryngomalacia (floppiness of tissue on top of the voice box that can possibly block breathing) found in association with obstructive sleep apnoea (blockage of breathing while sleeping). The purpose of this study is to determine which is the best treatment…
