Men's Health
01 Jan 2013
Methods Study to Characterize Early Indicators of Weight Loss in People.
This study will measure the changes that indicate successful weight loss in people. Official Title A Randomized, Open-Label, Parallel Group, Fixed Energy Deficit Methodology Trial to Characterize Early Efficacy Biomarkers During Treatment of Obesity in Adult, Obese, Male Subjects. Conditions Obesity Study Type Interventional Study Design Treatment, Randomized, Open…
Blood
01 Jan 2013
Study to Assess If Internet-Based Tailored Advice Could Modify Behaviour to Improve Health
The purpose of this trial is to find out if a special website might help people discover if they have high cholesterol and then enable them to manage their cholesterol more appropriately. The primary aim of this trial is to determine the effects on consumers’ use of cholesterol lowering therapy…
Hormones
01 Jan 2013
A 1-Year Study On The Effects Of CP-945,598 For The Treatment Of Obesity In Overweight Type 2 Diabetic Patients
The purpose of this study is to determine if CP-945,598 is effective in the treatment of obesity in type 2 diabetic patients. Official Title A 1-Year, Randomized, Double-Blind, Placebo-Controlled Phase 3 Study To Evaluate The Efficacy And Safety Of CP-945,598 In The Treatment Of Overweight, Oral Agent-Treated Subjects With Type…
Hormones
01 Jan 2013
Comparison of Two Approaches to Insulin Therapy in Patients With Type 2 Diabetes
A study of patients with type 2 diabetes who are not controlled on two or more oral antihyperglycemic agents comparing adding insulin lispro mid mixture to the oral antihyperglycemic agents to adding insulin glargine to the oral antihyperglycemic agents. Official Title Comparison of Two Approaches to Basal-Bolus Insulin Therapy in…
Hormones
01 Jan 2013
Blood Pressure and Glucose Lowering for the Prevention of Vascular Disease in High Risk Patients With Type 2 Diabetes.
The purpose of this study is to provide information on the risks and benefits of routine blood pressure lowering (regardless of blood pressure level), and intensive lowering of blood glucose levels, in patients with Type 2 diabetes at high risk of cardiovascular events. The major outcomes of the study will…
Hormones
01 Jan 2013
GALLANT 22 Tesaglitazar Vs. Placebo in Patients with Type 2 Diabetes
This is a 24-week randomized, double-blind, parallel-group, multi-center, placebo-controlled study of tesaglitazar (0.5 and 1 mg) in patients with type 2 diabetes, not adequately controlled on diet and lifestyle advice alone during the run-in period. The study comprises a 6-week single-blind placebo run-in period, followed by 24-week treatment period and…
Hormones
01 Jan 2013
Study Evaluating PPM-204 In Subjects With Type 2 Diabetes
The purpose of this study is to learn whether PPM-204 has an effect on lowering blood glucose (blood sugar) levels and is safe in treating people with type 2 diabetes. Official Title A 24-Week, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study Of The Safety And Efficacy Of PPM-204 In Subjects With Type…
Hormones
01 Jan 2013
A Study to Investigate the Effect of Rosuvastatin (CRESTOR) on High Density Lipoprotein Kinetics in Patients With the Metabolic Syndrome
The purpose of this study is to investigate the dose-related effect of treatment with rosuvastatin on production and fractional catabolism of apolipoprotein A-I (apoA-I) and apolipoprotein A-II (apoA-II), and on the plasma apoA-I, apoA-II and high-density lipoprotein cholesterol (HDL-C) concentration. Official Title A Randomised, Double-Blind, Placebo Controlled, Crossover Dose-Ranging Study…
Heart
01 Jan 2013
Can a Modified Fat Diet With Low Glycaemic Load Improve Insulin Sensitivity and Inflammatory Mediators in Overweight People With Chronic Heart Failure?
In overweight patients with chronic heart failure, to compare the effects of a modified fat diet with reduced glycaemic load (diet 1), and a conventional low fat, high carbohydrate diet (diet 2) on: insulin sensitivity (using the HOMA model); lipid profile; symptomatic status ( 6 minute walk distance and heart…
