Lungs
01 Jan 2013
Lung Volume Reductions Surgery (LVRS) Study
The main objectives of this study is to see if a type of lung surgery, known as lung reduction surgery, in addition to standard medical treatment improves the quality of life, lung function, and reduces the high mortality associated with severe emphysema when compared to standard medical treatment alone. Another…
Lungs
01 Jan 2013
Tissue Collection from People with Cystic Fibrosis
This study will examine the relationship between bacterial products in lung infections in cystic fibrosis and disease severity. It will examine plasma and lung tissue from cystic fibrosis patients. Official Title Tissue Collection Protocol for Individuals with Cystic Fibrosis Conditions Cystic Fibrosis Study Type Observational Study Design Natural History…
Gastro
01 Jan 2013
Supplemental Calcium in Overweight People
This study will examine the health effects of calcium supplements in overweight adults. Overweight adults often eat a diet low in calcium. Some studies have found low calcium intake in people who have some of the medical problems often seen in overweight adults. This study will see if extra calcium…
Gastro
01 Jan 2013
Study of Inborn Errors of Cholesterol Synthesis and Related Disorders
This study will investigate the cause and medical problems associated with a group of genetic disorders known as inborn errors of cholesterol synthesis, in which the body does not produce cholesterol. People with this disorder may have birth defects and learning and behavioral problems. Official Title Investigations into Inborn Errors…
Gastro
01 Jan 2013
Gluten-Free Diet in Patients with Gluten Sensitivity and Cerebellar Ataxia
This study will screen patients with cerebellar ataxia to check for antibodies that indicate allergy to gluten (wheat protein) and will study the effect of a gluten-free diet in patients with these antibodies. Patients with cerebellar ataxia have problems with coordination, resulting in “clumsiness” and unsteadiness of posture and walking.
Gastro
01 Jan 2013
Treatment of Hemochromatosis
This study will evaluate the effectiveness of a test called MCV in guiding phlebotomy (blood drawing) therapy in patients with hemochromatosis-an inherited disorder that causes too much iron to be absorbed by the intestine. The excess damages body tissues, most severely in the liver, heart, pancreas and joints. Because iron…
Lungs
01 Jan 2013
Studying Patients with Cystic Fibrosis and Other Pulmonary and Pancreatic Disorders
Cystic fibrosis is a disease that affects many parts of the body, particularly the lungs and pancreas. The main purpose of this study is to further understand the natural history, clinical presentation, and genetics of cystic fibrosis. Official Title Diagnosis and Treatment of Patients with Cystic Fibrosis and Other Disorders…
Lungs
01 Jan 2013
Epidemiology of Surfactant Protein-B Deficiency
To determine the impact of surfactant protein B genetic mutations on the risk of respiratory distress syndrome in infancy. Official Title Conditions – Lung Diseases- Respiratory Distress Syndrome Study Type Observational Study Design Natural History, Case Control Further Details BACKGROUND: Respiratory distress syndrome (RDS) is a common cause…
Infections
01 Jan 2013
Daily Isoniazid to Prevent Tuberculosis in Infants Born to Mothers with HIV
HIV infected women in South Africa have a high risk of tuberculosis (TB) infection. Children born to HIV infected mothers may be more likely to be exposed to and become infected with TB, and children infected with TB have a higher risk of developing severe disease than adults with TB.
