Gastro
01 Jan 2013
Probiotic and Crohn’s Disease Study
Probiotics are a food supplement containing living microorganisms, which upon ingestion in certain numbers exert health benefits beyond inherent basic nutrition. They have been shown to reduce intestinal inflammation in the inflammatory bowel diseases, Crohn’s disease (CD) and ulcerative colitis (UC). Probiotics are effective in the treatment of acute pouchitis…
Infections
01 Jan 2013
Study of Viramidine to Ribavirin in Patients with Chronic Hepatitis C Who Are Treatment Naive
The purpose of this study is to determine the safety and effectiveness of viramidine to ribavirin in chronic hepatitis C patients who have never before received treatment. Official Title Randomized, Double-Blind, Multicenter Study to Compare the Safety and Efficacy of Viramidine to Ribavirin in Treatment-Naive Patients With Chronic Hepatitic C…
Cancer
01 Jan 2013
A Feasibility Study to Evaluate Adjuvant Chemoradiotherapy for Gastric Cancer
The purpose of this study is to determine the side-effects and effectiveness of a new type of chemoradiotherapy treatment for patients who have had surgery for stomach cancer. The treatment uses epirubicin, cisplatin, and 5-fluorouracil (ECF) chemotherapy together with radiotherapy. Official Title Conditions Gastric Cancer Study Type Interventional Study Design…
Heart
01 Jan 2013
Follow-Up Serial Infusions of Natrecor(R) (Nesiritide) for the Management of Patients with Heart Failure-FUSION II
The purpose of this study is to evaluate the efficacy and safety of Natrecor(R) administered as serial infusions to heart failure (HF) patients in the outpatient setting. Official Title Conditions Heart Failure, Congestive Study Type Interventional Study Design Treatment, Randomized, Double-Blind, Placebo Control, Single Group Assignment, Safety/Efficacy Study Further…
Heart
01 Jan 2013
A Comparison of CS-747 and Clopidogrel in Acute Coronary Syndrome Subjects Who Are to Undergo Percutaneous Coronary Intervention
The sponsors of this investigational drug are developing prasugrel as a possible treatment for patients with acute coronary syndrome (heart attack or chest pain) who need, or are expected to need, a percutaneous coronary intervention (PCI; also called a balloon angioplasty). Prasugrel will be compared with clopidogrel to determine which…
Cancer
01 Jan 2013
Outcomes of Concurrent Chemo-Radiotherapy in Locally Advanced Cervical Cancer.
CCRT is considered the standard of care in LACC since 1999. However there are few reports of results of this treatment in the common practice in developing countries were this disease is most frequent. Official Title Outcomes of Concurrent Chemo-Radiotherapy (CCRT) in Locally Advanced Cervical Cancer (LACC). Results of a…
Cancer
01 Jan 2013
Combination chemotherapy of docetaxel, ifosfamide and cisplatin (DIP) in patients with metastatic urothelial cancer
The aim of this study was to evaluate the efficacy and toxicity of a new combination chemotherapy of docetaxel, ifosfamide and cisplatin (DIP) in the treatment of metastatic urothelial cancer. Official Title Combination chemotherapy of docetaxel, ifosfamide and cisplatin (DIP) in patients with metastatic urothelial cancer: a preliminary report. Conditions…
Cancer
01 Jan 2013
Study of irinotecan (CPT-11) combined with fixed dose of 5-fluorouracil (5-FU) adult patients with advanced solid tumours
Advanced solid tumors (gastrointestinal incl. Colorectal, head & neck, others) (1): to find the maximum tolerated dose (MTD) of the combined chemotherapy. (2): to determine the quantitive and qualitative toxic effects, the Dose-limiting toxicity and the recommended dose for phase II trials. (3): to define the safety profile…
Cancer
01 Jan 2013
Irinotecan (CPT-11)-based chemotherapy as induction treatment for advanced colorectal cancer
Advanced colorectal cancer (ACRC) To determine complete resection (R0), response rate, time to progression (TTP) and overall survival (OS) in patients with non-resectable ACRC after being treated with neoadjuvant irinotecan-based chemotherapy. Official Title Conditions Study Type Retrospective analysis Study Design Further Details Treatment Details:Irinotecan 250 mg/m2 i.v. (1h)…
