Cancer
01 Jan 2013
Nexavar-Tarceva Combination Therapy for First Line Treatment of Patients Diagnosed With Hepatocellular Carcinoma
This is a randomised trial to evaluate the clinical benefit of sorafenib and erlotinib versus sorafenib and placebo in subjects with unresectable advanced or metastatic Child-Pugh A…
Heart
01 Jan 2013
The Effect of Atorvastatin on Postoperative Renal Function After Cardiac Surgery
Atorvastatin might reduce the oxidative stress that occurs during cardiopulmonary bypass, and thus, prevent or reduce the magnitude of acute kidney dysfunction in those patients…
Mental Health
01 Jan 2013
Ultrabrief Pulsewidth Electroconvulsive Therapy (ECT) (UB ECT)
Electroconvulsive Therapy (ECT) remains essential to contemporary psychiatric practice and is one of the safest and most effective treatments available for depression.
Research and Trials
01 Jan 2013
Techniques to Improve Efficacy of Second Trimester Medical Termination
Interruption of a pregnancy after 14 weeks gestation may be required when the foetus is dead, severely malformed or in cases of maternal illness.
Research and Trials
01 Jan 2013
Audit and Screening Study to Determine the Prevalence of Peripheral Arterial Disease (ACHILLES)
The primary objective of the study is to establish the prevalence of lower extremity peripheral arterial disease in subjects with cardiovascular disease risk factors but no…
Research and Trials
01 Jan 2013
Safety and Efficacy Study of MPC-4326 for Treatment of Patients With HIV-1 Infection
To evaluate the antiretroviral activity and safety of 200 mg BID and 300 mg BID doses of MPC-4326 administered as monotherapy for 14 days to…
Cancer
01 Jan 2013
A Study of Avastin (Bevacizumab) in Combination With Temozolomide and Radiotherapy in Patients With Newly Diagnosed Glioblastoma
This two-arm study will investigate the efficacy and safety of the addition of bevacizumab (Avastin) to the current standard of care (multimodality therapy of concurrent radiotherapy plus temozolomide followed by adjuvant temozolomide) as compared to the current standard of care alone. Patients will be randomly assigned to either the Avastin…
Children's health
01 Jan 2013
A Clinical Trial of CSL’s 2009 H1N1 Influenza Vaccine (CSL425) in Healthy Children
The purpose of this study is to determine whether CSL425 is a safe and effective vaccine for eliciting an immune response to H1N1 influenza in…
Research and Trials
01 Jan 2013
The PLATINUM Clinical Trial to Assess the PROMUS Element Stent System for Treatment of De Novo Coronary Artery Lesions
The purpose of this study is to evaluate the safety and effectiveness of the PROMUS ElementTM Everolimus-Eluting Coronary Stent System for the treatment of patients with up to 2 de novo atherosclerotic coronary artery lesions. Official Title PLATINUM: A Prospective, Randomized, Multicenter Trial to Assess an Everolimus-Eluting Coronary Stent System…
