Research and Trials
01 Jan 2013
Freedom Study: Myfortic in Kidney Transplant Patients
The primary objective of the study is to evaluate that 3 immunosuppressant regimens will have comparable kidney function results in kidney transplant patients. Official Title Study to Investigate the Clinical Outcomes of Different Regimens of ‘Myfortic’ in De Novo Kidney Tx Pts Using ‘Simulect’ and ‘Neoral’ With or Without Steroids…
Heart
01 Jan 2013
Study of the Effect of Alendronate on Vascular Calcification and Arterial Stiffness in Chronic Kidney Disease
We aim to perform a prospective, randomised study assessing the impact of alendronate on cardiovascular and bone mineral parameters. This will be a single-centre study involving subjects with CKD Stage 3 (those patients with GFR between 30 and 59ml/min). Arterial stiffness (by pulse wave analysis and pulse wave velocity) and…
Research and Trials
01 Jan 2013
A Study of BMS-224818 (Belatacept) in Patients Who Have Undergone a Kidney Transplant and Are Currently on Stable Cyclosporine or Tacrolimus Regimen With or Without Corticosteroids
The purpose of this study is to learn if conversion to belatacept from cyclosporine or tacrolimus will preserve kidney function in people who have had a kidney transplant. The safety of this treatment will also be studied Official Title Belatacept Conversion Trial in Renal Transplantation Conditions Renal Transplant Study Type…
Research and Trials
01 Jan 2013
Open Label Tolerability and Safety Study of KRX-101 in Australia, New Zealand, and Hong Kong
The purpose of this study is to assess the tolerability and safety of KRX-101 in treating persistent microalbuminuria in type 2 diabetic patients who are also being treated with stable, maximum tolerated doses of either ACE inhibitors or A2 receptor blockers. Official Title An Open Label Tolerability and Safety Study…
Research and Trials
01 Jan 2013
Using the Drug Spironolactone to Test If It Reduces Protein Leakage From the Kidney
The purpose of this study is to determine which combination of the tablets ramipril, irbesartan or spironolactone is best to lower protein leakage from the kidney. Protein leak from the kidney into the urine is an indicator of kidney damage. The higher the leak, the worse the damage and the…
Research and Trials
01 Jan 2013
Short Term Effects of FX Dialysers on QOL and Inflammation
This study aims to assess the short-term effects of the FX-class Dialyser on quality of life and inflammatory markers in stable haemodialysis patients with chronic kidney failure. Official Title Short-Term Effects of the FX-Class of Haemodialyser on Quality of Life and Inflammatory Markers in Stable Dialysis Patients. Conditions Kidney Failure,…
Blood
01 Jan 2013
A Prospective, Surveillance Study to Estimate the Incidence of Pure Red Blood Cell Aplasia (Aplastic Anemia) Mediated by Erythropoietin Antibodies Among Patients With Chronic Kidney Failure and Subcutaneous Exposure to Recombinant Erythropoietin Prod
The purpose of this study is to estimate the incidence rate of pure red cell aplasia (PRCA; aplastic anemia) mediated by erythropoietin (EPO) antibodies in patients who are receiving subcutaneous (s.c.) EPREX (polysorbate 80 formulation) for the treatment of anemia associated with chronic renal failure (CRF), and to compare this…
Research and Trials
01 Jan 2013
Augmented Vs. Normal Renal Replacement Therapy in Severe Acute Renal Failure (ARF)
This study seeks to determine if increasing the dose of continuous renal replacement therapy (CRRT) reduces 90-day all cause mortality in Intensive Care Unit (ICU) patients with severe acute renal failure (ARF). Official Title Multicentre, Unblinded, Open Label, Randomised, Controlled Trial to Assess the Effect of Augmented Vs. Normal Continuous…
Heart
01 Jan 2013
A Trial of INO-1001 in Patients Undergoing Heart Surgery That Involves Heart-Lung Bypass
The purpose of this study is to assess the safety of INO-1001, an intravenous PARP (poly-polymerase) inhibitor, in patients undergoing heart surgery. The study also measures whether INO-1001 reduces the side effects caused by heart-lung bypass machines. Official Title A Phase II Randomized, Double-Blind, Placebo-Controlled, Multi-Center Study to Evaluate Tolerability,…
