Hormones
01 Jan 2013
Study Evaluating PPM-204 In Subjects With Type 2 Diabetes
The purpose of this study is to learn whether PPM-204 has an effect on lowering blood glucose (blood sugar) levels and is safe in treating people with type 2 diabetes. Official Title A 24-Week, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study Of The Safety And Efficacy Of PPM-204 In Subjects With Type…
Hormones
01 Jan 2013
Lanreotide Autogel in Patients With Acromegaly Previously Treated With Octreotide LAR
The purpose of this study is to assess the efficacy, safety and patient acceptability of Somatuline Autogel in patients with acromegaly previously treated with octreotide LAR. Official Title A Phase IV, Multicentre, Open-Label, Single Group Study to Evaluate the Dosing, Efficacy and Safety of Lanreotide Autogel in Patients With Acromegaly…
Hormones
01 Jan 2013
E.V.O.L.V.E. Trial: EValuation Of Cinacalcet HCl Therapy to Lower CardioVascular Events
This study will evaluate the effects of cinacalcet (cincalcet HCl or Sensipar/Mimpara) on cardiovascular events and death in chronic kidney disease (CKD) patients with secondary hyperparathryoidism (HPT) who are receiving dialysis. Official Title EValuation Of Cinacalcet HCl Therapy to Lower CardioVascular Events Conditions Secondary Hyperparathyroidism, Chronic Kidney Disease Study Type…
Children's health
01 Jan 2013
Predictive Markers in GHD and TS Children Treated With ‘SAIZEN’
The study aims at identifying the predictive markers after one month of Saizen therapy in Growth Hormone Deficiency (GHD) and Turner Syndrome children. The study will recruit approximately 360 children in several countries worldwide. The study lasts for about the first one month of daily growth hormone treatment. There will…
Hormones
01 Jan 2013
A Study to Investigate the Effect of Rosuvastatin (CRESTOR) on High Density Lipoprotein Kinetics in Patients With the Metabolic Syndrome
The purpose of this study is to investigate the dose-related effect of treatment with rosuvastatin on production and fractional catabolism of apolipoprotein A-I (apoA-I) and apolipoprotein A-II (apoA-II), and on the plasma apoA-I, apoA-II and high-density lipoprotein cholesterol (HDL-C) concentration. Official Title A Randomised, Double-Blind, Placebo Controlled, Crossover Dose-Ranging Study…
Hormones
01 Jan 2013
Comparison of Insulin Detemir With NPH Insulin in Type 1 Diabetes
The aim of this research study is to compare the efficacy (reduction in HbA1c and in blood glucose levels) of insulin detemir compared to NPH insulin administered as basal insulin for the treatment of type 1 diabetes and to verify the safety of use (number and severity of episodes of…
Children's health
01 Jan 2013
Trial of Intranasal Insulin in Children and Young Adults at Risk of Type 1 Diabetes
In people with type I diabetes the beta cells of the pancreas no longer make insulin because the body’s immune system has attacked and destroyed the beta cells. It is thought that exposure of the mucous membranes to insulin may cause act like a vaccine effect whereby protective immune cells…
Hormones
01 Jan 2013
Comparison of Two Basal Insulin Therapies for Patients With Type 1 Diabetes (IOOZ)
The purpose of this study is to examine the effectiveness and safety of lispro protamine suspension as compared to insulin detemir as basal plus mealtime insulin therapy in patients with type 1 diabetes. Official Title Comparison of Two Basal Insulin Analogs (Insulin Lispro Protamine Suspension and Insulin Detemir) in Basal-Bolus…
Hormones
01 Jan 2013
Thyroid-Associated Ophthalmopathy Subtypes and Orbital Antibodies in patients with hyperthyroidism due to Graves’ disease
The purpose of this study is to determine whether radioactive iodine, as compared to anti-thyroid medications, is a risk factor for the development or progression of thyroid-associated ophthalmopathy in patients with hyperthyroidism due to Graves’ disease. The other aim of this study is to determine the incidence of the various…
