Bone
01 Jan 2013
Zoledronic Acid Treatment of Spontaneous Osteonecrosis of the Knee
This study will assess the safety and efficacy of zoledronic acid in patients presenting with spontaneous osteonecrosis of the knee. Official Title A Randomized, Double-Blind, Placebo-Controlled, Proof of Concept Study of Zoledronic Acid in Spontaneous Osteonecrosis of the Knee (SONK) Conditions Osteonecrosis Study Type Interventional Study Design Treatment, Randomized, Double-Blind,…
Bone
01 Jan 2013
A Study to Assess the Efficacy of Intravenous Bondronat (Ibandronate) in Patients With Malignant and Painful Bone Disease
This study will compare the efficacy of intravenous Bondronat with that of zoledronic acid in patients with malignant bone disease experiencing moderate to severe pain. The anticipated time of study treatment is 6-12 months, and the target sample size is 100-500 individuals Official Title A Randomized, Placebo-Controlled, Double-Blind Study of…
Bone
01 Jan 2013
Long Term Efficacy and Safety of Zoledronic Acid Treatment in Patients With Bone Metastases
This study is designed to monitor the safety and efficacy of long-term treatment with zoledronic acid by assessing the incidence of, renal impairment, osteonecrosis of the jaw(ONJ), overall safety and skeletal related events (SREs) beyond 12 months treatment Official Title A Phase IV Study of Zoledronic Acid Therapy in Patients…
Bone
01 Jan 2013
Combination Chemotherapy With or Without Peripheral Stem Cell Transplantation, Radiation Therapy, and/or Surgery in Treating Patients With Ewing’s Sarcoma
This randomized phase III trial is studying different combination chemotherapy regimens to see how well they work when given with or without peripheral stem cell transplantation, radiation therapy, and/or surgery in treating patients with Ewing’s sarcoma Official Title EURO-E.W.I.N.G. 99 – European Ewing Tumour Working Initiative of National Groups –…
Bone
01 Jan 2013
Study Evaluating the Safety and Efficacy of a Once-Daily Dose of Tigecycline vs Ertapenem in Diabetic Foot Infections with Osteomyelitus
This purpose of this study is to look at the safety and effectiveness of a once-daily dose of tigecycline compared to ertapenem for the treatment of diabetic foot infections with osteomyelitis. Official Title A Multicenter, Randomized, Double-Blind, Comparison Study of the Safety and Efficacy of a Once-Daily Dose of Tigecycline…
Bone
01 Jan 2013
Trial of Physiotherapy and Corticosteroid Injections in Lateral Epicondylalgia
This randomised controlled trial will evaluate the role of manual therapy and therapeutic exercise and corticosteroid injections in the treatment of lateral epicondylalgia (tennis elbow). Official Title A Pragmatic, Randomised Controlled Trial of Physiotherapy and Corticosteroid Injections in Lateral Epicondylalgia Conditions Tennis Elbow, Musculoskeletal Diseases Study Type Interventional Study Design…
Research and Trials
01 Jan 2013
Effect of Teriparatide Compared to Risedronate on Back Pain in Women With a Spine Fracture Caused by Osteoporosis
The purpose of the study is to determine if daily teriparatide reduces back pain more effectively than weekly risedronate in postmenopausal women with osteoporosis that have back pain due to a spinal bone fracture. Official Title The Effect of Teriparatide Compared With Risedronate on Back Pain in Postmenopausal Women With…
Research and Trials
01 Jan 2013
A Study to Evaluate AMG 162 in the Treatment of Postmenopausal Osteoporosis
This study will evaluate the effectiveness and safety of AMG 162 in treating women with Postmenopausal Osteoporosis. Official Title Conditions Osteoporosis Study Type Interventional Study Design Treatment Further Details Primary Outcome Measures: Reduction in the number of new vertebral fractures in post menopausal osteoporotic women treated with AMG…
Cancer
01 Jan 2013
GW786034 In Subjects With Locally Recurrent Or Metastatic Clear Cell Renal Cell Carcinoma
Phase II, multi-center, two-stage study utilising a randomised discontinuation design to evaluate the safety and efficacy of GW786034 in adult subjects with locally recurrent or metastatic clear-cell Renal Cell Carcinoma (RCC). Official Title A Phase II Study of GW786034 Using a Randomised Discontinuation Design in Subjects With Locally Recurrent or…
