Gastro
01 Jan 2013
A Study of Abatacept in Patients With Active Crohn’s Disease
The purpose of this clinical research study is to learn if abatacept can improve signs and symptoms of active Crohn’s Disease in patients who have not had an adequate response to other therapies. The safety of this treatment will also be studied. Official Title A Phase 3, Multi-Center, Randomized, Placebo-Controlled…
Gastro
01 Jan 2013
Study of Dexlansoprazole vs Placebo on the Ability to Maintain Healing in Subjects With Healed Erosive Esophagitis.
A 6-month study to assess the ability of daily treatment with dexlansoprazole 30mg, 60 mg or placebo in maintaining healing of erosive esophagitis. Official Title A Phase 3 Study to Evaluate the Safety and Efficacy of TAK-390MR (30 mg QD and 60 mg QD) Compared to Placebo in Maintenance of…
Gastro
01 Jan 2013
Study of Esomeprazole 20 mg or 40 mg vs Placebo Effectiveness on the Occurrence of Peptic Ulcers in Subjects on LDA (Oberon)
The purpose of this study is to compare the effect of esomeprazole 20 and 40 mg once daily versus placebo on the occurrence of peptic ulcers during 26 weeks in subjects on continuous low-dose acetylsalicylic acid. Official Title A Randomized, Double-Blind, Parallel-Group, Multicentre, Phase III Study to Assess the Effect…
Blood
01 Jan 2013
Study to Assess If Internet-Based Tailored Advice Could Modify Behaviour to Improve Health
The purpose of this trial is to find out if a special website might help people discover if they have high cholesterol and then enable them to manage their cholesterol more appropriately. The primary aim of this trial is to determine the effects on consumers’ use of cholesterol lowering therapy…
Blood
01 Jan 2013
Efficacy and Safety of Colesevelam in Pediatric Patients With Genetic High Cholesterol
This study will evaluate the lipid-lowering effect and safety of colesevelam therapy administered to heterozygous familial pediatric patients 10 through 17 years of age who are on a stable dose of a pediatric-approved statin monotherapy (atorvastatin, lovastatin, simvastatin or pravastatin), or who are treatment naive to lipid-lowering therapy. Official Title…
Blood
01 Jan 2013
Combination Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Children With Recurrent or Refractory Hodgkin’s or Non-Hodgkin’s Lymphoma
Phase II trial to study the effectiveness of combination chemotherapy followed by peripheral stem cell transplantation in treating children who have recurrent or refractory Hodgkin’s lymphoma or non-Hodgkin’s lymphoma. Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Peripheral stem…
Blood
01 Jan 2013
PRELUDE:Study to Investigate the Prevention of Relapse in Lymphoma Using Daily Enzastaurin
This clinical research study is to investigate the prevention of relapse in patients with diffuse large B cell lymphoma (DLBCL) using enzastaurin daily. This is a randomised trial which compares Enzastaurin to Placebo (dummy treatment), the chance of receiving Enzastaurin is 2 to 1. Official Title A Phase 3…
Blood
01 Jan 2013
Ig NextGen 10% in ITP Patients
Idiopathic Thrombocytopenic Purpura (ITP) is an autoimmune bleeding disorder characterised by isolated low platelet counts. The aim of treating patients with ITP is to increase the platelet concentration and reduce the risk of bleeding. A number of controlled multi-centre studies have demonstrated that Intravenous Immunoglobulin (IVIg) therapy produces a rapid…
Blood
01 Jan 2013
Odiparcil For The Prevention Of Venous Thromboembolism
Odiparcil is being studied to determine if it can prevent blood clots from forming after a total knee replacement and also to prove that odiparcil is safe. Official Title A Dose Ranging Trial for the Evaluation of the Safety, Tolerability and Efficacy of Odiparcil in the Prevention of Venous Thromboembolism…
