Mental Health
01 Jan 2013
Serotonin Function During Depression
Serotonin is a chemical involved in regulation of emotions, anxiety, sleep, stress hormones, and other body functions. The purpose of this study is to use a procedure called tryptophan depletion to study the function of serotonin in people with depression and in healthy volunteers. Official Title Tryptophan Depletion and PET…
Mental Health
01 Jan 2013
Brain Imaging in Depression
The purpose of this study is to use brain imaging technology to examine the role of certain brain receptors and the nervous system chemical acetylcholine in major depression. Official Title Muscarinic Cholinergic Receptor Imaging in Depression Conditions – Depression- Bipolar Disorder Study Type Observational Study Design Natural History Further…
Mental Health
01 Jan 2013
Clinical Trial of Memantine for Major Depression
The purpose of this study is to determine the safety and effectiveness of the drug memantine for treating major depression. The purpose of this study is to determine the safety and effectiveness of the drug memantine for treating major depression.Major depression is a serious public health concern that contributes to…
Mental Health
01 Jan 2013
Clinical Trial of Tolcapone for Cognition in Schizophrenia
The purpose of this study is to test whether the drug tolcapone improves the memory of patients with schizophrenia. The purpose of this study is to test whether the drug tolcapone improves the memory of patients with schizophrenia.The catecholaminergic system can enhance some aspects of cognitive function, such as working…
Mental Health
01 Jan 2013
Treatment for First-Episode Schizophrenia
The purpose of this study is to see if the newest class of antipsychotic medications can improve the course of patients with first-episode schizophrenia. Official Title Preventing Morbidity in First-Episode Schizophrenia Conditions – Schizophrenia Study Type Interventional Study Design Treatment, Randomized Further Details Schizophrenia patients generally respond very well…
Mental Health
01 Jan 2013
Genetic Study of Schizophrenia
The purpose of this study is to understand the role of genetics in the development of schizophrenia by studying heritable traits in families where at least one member has schizophrenia. Official Title A Neurobiological Investigation of Patients with Schizophrenia Spectrum Disorders and Their Siblings Conditions – Psychotic Disorder- Schizoaffective Disorder-…
Gastro
01 Jan 2013
Cognitive Therapy for Binge-Eating Disorder
The purpose of this study is to compare the efficacy of a CD-ROM-based cognitive-behavioral therapy (CBT) to traditional manual-based group therapy for obese individuals with binge-eating disorder (BED) and other unhealthy eating behaviors. A second goal is to encourage a healthy lifestyle in patients with BED. Official Title Cognitive Therapy…
Mental Health
01 Jan 2013
Vitamin E in Aging Persons With Down Syndrome
The goal of this study is to determine the safety and efficacy of the administration of vitamin E, which has been shown to delay the progression of Alzheimer’s disease, in slowing the rate of cognitive/functional decline in older persons with Down syndrome. Official Title Multicenter Vitamin E Trial in Aging…
Mental Health
01 Jan 2013
Molecular Genetics of Schizophrenia
This study will orgnaize and release previously-obtained data from a DNA collection used to search for schizophrenia-related genes. The data will be made available to the scientific community for genetic studies of schizophrenia and related disorders. Official Title Conditions – Schizophrenia Study Type Observational Study Design Natural History…
