Heart
01 Jan 2013
Panic Disorder and Cardiac Risk
The reason for increased cardiac mortality in panic disorder has not been precisely identified, but possibly is due to chronic activation of the cardiac stimulant (sympathetic) nerves, which may predispose the individual with panic disorder to disorders of cardiac rhythm and coronary artery spasm. The uniqueness of this study lies…
Mental Health
01 Jan 2013
An Eight-Week Study to Evaluate the Efficacy and Safety of 2 Doses of Saredutant in Patients With Generalized Anxiety Disorder
The primary objective is to evaluate the efficacy of two fixed doses (100 mg and 30 mg once daily) of saredutant compared to placebo in patients with generalized anxiety disorder. The secondary objectives are to evaluate the efficacy of saredutant on disability and quality of life in patients with generalized…
Blood
01 Jan 2013
Levosimendan versus Dobutamine in Shock Patients
The purpose of the study is to compare the efficacy of levosimendan with that of dobutamine in patients with unstable hemodynamics (shock). Official Title Efficacy of Levosimendan in the Critically Ill Patients with Unstable Hemodynamics (the LICI study) – A Double Blind Randomized Pilot Study Conditions – Cardiogenic Shock-…
Children's health
01 Jan 2013
An Outpatient Study of the Effectiveness and Safety of Depakote ER in the Treatment of Mania/Bipolar Disorder in Children and Adolescents
The purpose of this study is to determine the safety and effectiveness of Depakote ER (Divalproex Sodium Extended-Release Tablets) compared to placebo in the treatment of bipolar disorder, manic or mixed type in children and adolescents ages 10-17 years. Official Title Conditions Bipolar Disorder Study Type Interventional Study Design Treatment…
Mental Health
01 Jan 2013
Comparison of Intramuscular Olanzapine Depot to Oral Olanzapine and Low-Dose Depot in the Maintenance Therapy of Patients With Schizophrenia
Key objectives of this clinical study are to: – Determine how well intramuscular (IM) olanzapine depot works compared to oral olanzapine – Evaluate the safety and tolerability of IM olanzapine depot compared to oral olanzapine – Evaluate different doses of IM olanzapine depot to identify the best dose(s)…
Children's health
01 Jan 2013
Quetiapine Fumarate (SEROQUEL) Compared to Placebo in the Treatment of Children and Adolescent Patients with Bipolar I Mania
The purpose of this study is to demonstrate efficacy and safety of quetiapine fumarate (SEROQUEL) compared with placebo in the treatment of children and adolescent patients with Bipolar I mania. Official Title Conditions Bipolar Disorder Study Type Interventional Study Design Treatment, Placebo Control, Safety/Efficacy Study Further Details Study Start…
Mental Health
01 Jan 2013
Duloxetine Compassionate Use in Patients Who Have Completed a Previous Neuroscience Duloxetine Clinical Trial
The primary objective of this study is to provide duloxetine to investigators for the treatment of patients who have previously participated in neuroscience duloxetine clinical trials and for whom effective alternative therapy is not available. Official Title Open Label Duloxetine Compassionate Use in Patients Who Have Completed a Previous Neuroscience…
Mental Health
01 Jan 2013
Efficacy and Safety of Aricept in the Treatment of Severe Alzheimer’s Disease
Donepezil hydrochloride (Aricept) has been approved to treat symptoms associated with mild to moderate Alzheimer’s disease (AD). Aricept has been shown to improve the memory and thinking abilities, activities of daily living and global function in patients. The purpose of the study is to further investigate the effectiveness and safety…
Mental Health
01 Jan 2013
Clinical Trial of Pramipexole in Bipolar Depression
The purpose of this study is to examine the safety and effectiveness of the drug pramipexole given in combination with lithium or divalproex for the short-term treatment of acute depression in patients with bipolar disorder. Bipolar disorder is a severe, chronic, and often life-threatening illness. Treatments for acute unipolar…
