Lungs
01 Jan 2013
Treatment of Pulmonary Sarcoidosis with Pentoxifylline
Sarcoidosis is a disease most commonly affecting the lungs, but it can also involve lymph nodes, skin, liver, spleen, eyes, bones, and glands. The cause of the disease is unknown. When it occurs it can produce an inflammatory reaction leading to irreversible organ damage and disability. Official Title Conditions –…
Lungs
01 Jan 2013
Lung Volume Reductions Surgery (LVRS) Study
The main objectives of this study is to see if a type of lung surgery, known as lung reduction surgery, in addition to standard medical treatment improves the quality of life, lung function, and reduces the high mortality associated with severe emphysema when compared to standard medical treatment alone. Another…
Lungs
01 Jan 2013
Tissue Collection from People with Cystic Fibrosis
This study will examine the relationship between bacterial products in lung infections in cystic fibrosis and disease severity. It will examine plasma and lung tissue from cystic fibrosis patients. Official Title Tissue Collection Protocol for Individuals with Cystic Fibrosis Conditions Cystic Fibrosis Study Type Observational Study Design Natural History…
Lungs
01 Jan 2013
Studying Patients with Cystic Fibrosis and Other Pulmonary and Pancreatic Disorders
Cystic fibrosis is a disease that affects many parts of the body, particularly the lungs and pancreas. The main purpose of this study is to further understand the natural history, clinical presentation, and genetics of cystic fibrosis. Official Title Diagnosis and Treatment of Patients with Cystic Fibrosis and Other Disorders…
Lungs
01 Jan 2013
Epidemiology of Surfactant Protein-B Deficiency
To determine the impact of surfactant protein B genetic mutations on the risk of respiratory distress syndrome in infancy. Official Title Conditions – Lung Diseases- Respiratory Distress Syndrome Study Type Observational Study Design Natural History, Case Control Further Details BACKGROUND: Respiratory distress syndrome (RDS) is a common cause…
Infections
01 Jan 2013
Daily Isoniazid to Prevent Tuberculosis in Infants Born to Mothers with HIV
HIV infected women in South Africa have a high risk of tuberculosis (TB) infection. Children born to HIV infected mothers may be more likely to be exposed to and become infected with TB, and children infected with TB have a higher risk of developing severe disease than adults with TB.
Lungs
01 Jan 2013
Role of T-Cells in Asthma
This study will examine the movement of T cells (a type of white blood cell) from the blood to the lungs in patients with asthma after exposure to an allergen, such as cat dander or pollen. Asthma is in large part due to inflammation of the bronchi (the breathing tubes…
Lungs
01 Jan 2013
Childhood Asthma Research and Education (CARE) Network
To evaluate current and novel therapies and management strategies for children with asthma. The emphasis is on clinical trials that help identify optimal therapy for children with different asthma phenotypes, genotypes, and ethnic backgrounds and children at different developmental stages. Official Title Conditions – Asthma- Lung Diseases Study Type…
Lungs
01 Jan 2013
Pollutant altered allergic response
This study is designed to investigate whether exposure to particulate air pollution increases the allergic response to allergens. Research studies suggest that symptoms in individuals with allergies may be aggravated by exposure to particulate air pollution. We sought to experimental determine this by exposing human volunteers to combustion particles, a…
