Hormones
01 Jan 2013
Comparing Exenatide and Insulin Glargine in Type 2 Diabetes Patients for Whom Insulin is the Next Appropriate Therapy
This is a study with two treatment sequences and two treatment periods that will assess the safety and efficacy of exenatide treatment in patients with type 2 diabetes who have inadequate glycemic control using metformin or sulfonylurea and for whom insulin is the next appropriate step in diabetes treatment. Official…
Hormones
01 Jan 2013
Reduction in the Occurrence of Center-Threatening Diabetic Macular Edema
The purpose of this study is to determine if ruboxistaurin can help slow the worsening of an eye disease called macular edema in patients with diabetes. Official Title Conditions Diabetic Retinopathy Study Type Interventional Study Design Treatment Further Details Study Start Eligibility & Criteria Inclusion Criteria:- You must have…
Bone
01 Jan 2013
A Study to Compare the Efficacy and Safety of Pegvisomant to that of Sandostatin LAR in Patients with Acromegaly
The pupose of the study is to determine if Pegvisomant is more efficacious than Sandostatin LAR Depot in normalizing IGF-I levels in treatment naive patients with acromegaly. Condition:- Acromegaly Study Type: InterventionalStudy Design: Treatment Eligibility Ages Eligible for Study: 18 Years and above, Genders Eligible for Study: Both Criteria Other…
Bone
01 Jan 2013
Pegvisomant and Sandostatin LAR Combination Study
To compare the safety and tolerability of combination therapy with Sandostatin LAR plus Pegvisomant to that of Sandostatin LAR alone or Pegvisomant alone. To compare the safety and tolerability of combination therapy with Sandostatin LAR plus Pegvisomant to that of Sandostatin LAR alone or Pegvisomant alone.Condition:- AcromegalyStudy Type: InterventionalStudy Design:…
Bone
01 Jan 2013
The Treatment and Natural History of Acromegaly
This study is directed toward acromegaly and treatment of patients with acromegaly. Acromegaly is a condition due to high levels of growth hormone in the blood. Growth hormone is responsible for the regulation of the metabolism of sugar, fat, and protein. When growth hormone levels are elevated patients may experience…
Heart
01 Jan 2013
Registry of Fabry Disease – A Multicenter Observational Study
The purpose of this study is to compile a registry of patients with Fabry disease, an inherited metabolic disorder. In this disease, an enzyme called a-galactosidase A, which normally breaks down a lipid (fatty substance) called globotriaosylceramide (Gb3), is missing or does not function properly. As a result, Gb3 accumulates,…
Hormones
01 Jan 2013
Turner Syndrome: Genotype and Phenotype
This study will examine the clinical and genetic factors related to Turner syndrome, a disorder of the female sex chromosomes. Humans have 23 pairs of chromosomes-thin strands of DNA-in the nucleus of every cell, which contain genes that determine our hereditary makeup. One pair of chromosomes is the sex chromosomes,…
Hormones
01 Jan 2013
Treatment of Peripheral Neuropathy in Patients with Diabetes.
The purpose of this protocol is to determine if an investigational drug is effective in treating nerve malfunction in diabetes. Condition: – Diabetic Neuropathies – Diabetes Mellitus The purpose of this protocol is to determine if an investigational drug is effective in treating nerve malfunction in diabetes.Condition: –…
Hormones
01 Jan 2013
A Study To Evaluate The Safety And Efficacy Of An Investigational Diabetes Drug In Poorly Controlled Type II Diabetics
The purpose of this research study is to determine if a new investigational diabetes drug is safe and effective in treating people who have Type II diabetes mellitus with very high HbA1c or FPG (fasting plasma glucose) levels. The HbA1c test, also called the hemoglobin A1c test or glycated hemoglobin…
