Children's health
12 Feb 2013
Avoid unneeded abdominal CT scans in children
A study of more than 12,000 children from emergency departments throughout the country in the Pediatric Emergency Care Applied Research Network (PECARN) has identified seven factors that can help physicians determine the need for a computed tomography (CT) scan following blunt trauma to the abdomen. Because CT scans pose radiation…
Children's health
01 Jan 2013
Metabolic Phenotyping of Individuals Born Following Assisted Reproduction Techniques (IMPART)
This study is to compare the effects of high-fat overfeeding on metabolic risk factors in children born through assisted reproduction technologies (ART) versus children conceived naturally (controls). We will utilise state of the art measures to characterise the physiological, endocrine and molecular responses to high fat overfeeding. The investigators…
Cancer
01 Jan 2013
Nexavar-Tarceva Combination Therapy for First Line Treatment of Patients Diagnosed With Hepatocellular Carcinoma
This is a randomised trial to evaluate the clinical benefit of sorafenib and erlotinib versus sorafenib and placebo in subjects with unresectable advanced or metastatic Child-Pugh A…
Gastro
01 Jan 2013
The Effects of Reducing Stomach Acid on Post-Tonsillectomy Pain
This study was designed to determine whether post-operative pain following a tonsillectomy can be reduced by adding an antacid-like medication to the medications taken after surgery. It is hypothesised that even a small amount of stomach acid backing up and entering the mouth can increase post-tonsillectomy pain. Therefore, the use…
Gastro
01 Jan 2013
Effect of Prevacid on Prostaglandin Levels in Patient With Stress Ulcer
The purpose of this study is to measure the prostaglandin levels in patients with stress ulcer and the effect of Prevacid on prostaglandin levels in patients with stress ulcer. Official Title Effect of Prevacid on Prostaglandin Levels in the Gastric Mucosa of Patients With Stress Ulcer. Conditions Stomach…
Cancer
01 Jan 2013
Trial of Adjuvant Chemotherapy for Gastric Cancer
This study is designed to evaluate the efficacy of the intraperitoneal chemotherapy with early mitomycin administration and adding cisplatin to prolonged treatment with doxifluridine compared to mitomycin plus doxifluridine in resected advanced gastric cancer. Official Title A Phase III Randomised Controlled Trial of Adjuvant Chemotherapy for Gastric Adenocarcinoma: Mitomycin and…
Gastro
01 Jan 2013
Truvada Versus Truvada Plus HBIG in Prevention of Chronic Hepatitis B Recurrence Post Liver Transplant
The objective of this study is to evaluate the safety and antiviral efficacy of the combination therapy (emtricitabine/tenofovir disoproxil fumarate), plus or minus Hepatitis B Immunoglobulin (HBIG) in preventing the recurrence of chronic hepatitis B after a patient (who was chronically infected with hepatitis B pre-liver transplant) has undergone a…
Gastro
01 Jan 2013
Optical Coherence Tomography of the Gastrointestinal Tract (OCT)
Optical coherence tomography (OCT) is a non-invasive imaging technique that uses light to create pictures of living tissues and has been successfully used to generate high resolution cross-sectional images of tissue in the human eye and skin. OCT systems are now commercially available for eye and skin use, and several…
Bone
01 Jan 2013
Hypovitaminosis D and an Inadequate PTH Response in Chronic Liver Disease Patients
The purpose of this study is to determine how common low levels of magnesium are in patients with end stage liver disease. In addition, investigator is trying to determine if low levels of magnesium affect the release of parathyroid hormone in patients with end stage liver disease and low vitamin…