Cancer
01 Jan 2013
Hair Loss through Chemotherapy & Feminity in Young Women
Aim: To explore the impacts of hair loss, through chemotherapy, on young women’s sense of femininity. Official Title Hair Loss through Chemotherapy: How Does It Affect A Young Person’s Sense Of Femininity? Conditions Study Type Exploratory Study Design This 4th year honours project is seeking assistance from 6 young female…
Cancer
01 Jan 2013
ZD4054 in Pain-Free or Mildly Symptomatic Patients With Prostate Cancer and Bone Metastases Who Have Rising Serum Prostate Specific Antigen (PSA)
This study is being carried out to see if ZD4054 is effective in treating prostate cancer and spread of cancer to the bone, and if so, how it compares with placebo (sugar pill). The study will also provide further information on the safety of ZD4054. Official Title Randomized, Double-Blind, Parallel-Group,…
Cancer
01 Jan 2013
Combination Chemotherapy and Radiation Therapy in Treating Patients With Acute Lymphoblastic Leukemia That Has Relapsed in the CNS or Testes
Rationale: Drugs used in chemotherapy work in different ways to stop cancer cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage cancer cells. Giving combination chemotherapy together with radiation therapy may kill more cancer cells. Purpose: This clinical trial is…
Bone
01 Jan 2013
Treatment of osteosarcoma at first recurrence after contemporary therapy
Aim: To determine the outcome for patients with recurrent OS who were treated at MSKCC at the time of first recurrence. Conclusions: At first recurrence, 22 of 31 patients achieved a CR2 with aggressive surgery and chemotherapy. The majority of these patients subsequently developed a disease recurrence. Patients appeared to…
Bone
01 Jan 2013
Tumour regression & tissue repair when ZOL is combined with IFO in rat osteosarcoma
Aim: To evaluate the efficacy of the combination of zoledronic acid (ZOL) with ifosfamide (IFO) on local tumor growth, histologic response, and animal survival using a rat-transplantable model of osteosarcoma. Conclusions: This is the first report of the anti-bone resorption and antitumoral activities of zoledronic acid in a rat model…
Cancer
01 Jan 2013
CIBO-P for pts with poor prognostic refractory or multiple disease recurrent aggressive NHL
Aim: To assess the activity and safety of a novel combination therapy for patients with recurrent or refractory aggressive NHL, to evaluate the long-term results, and identify prognostic factors in the study cohort. Conclusions: In the current study, CIBO-P was a novel, highly active, and safe combination therapy for patients…
Cancer
01 Jan 2013
IMVP-16/Pd followed by HDC/ASCT for relapsed peripheral T-cell lymphomas
Aim: To analyse the treatment outcome of IMVP-16/Pd (ifosfamide, methotrexate, etoposide and prednisone) followed by high-dose chemotherapy and autologous stem cell transplantation (HDC/ASCT) for patients with peripheral T-cell lymphomas (PTCLs) who were previously treated with CHOP. Conclusions: These results indicate that IMVP-16/Pd followed by HDC/ASCT appears to be an effective…
Cancer
01 Jan 2013
Phase 2 study of DICb in adv. NSCLC
Aim: To test the tolerability and activity of a novel regimen combining docetaxel instead of paclitaxel and carboplatin instead of cisplatin with ifosfamide (DICb) in the outpatient setting in patients with advanced non-small cell lung cancer. Conclusions: In the present phase II study the DICb combination yielded important activity and…
Cancer
01 Jan 2013
CEBOPP/VIML Followed by Radiotherapy for Intermediate- and Advanced-Stage HD
Aim: To improve treatment results and minimize acute and late toxicity in patients (pts) with intermediate- or advanced-stage Hodgkin’s disease. A combined modality treatment consisting of a response-adapted chemotherapy (CTX) and radiotherapy (RTX) was used. Conclusions: CEBOPP/VIML followed by RTX appears to be highly effective in achieving long-term…
